Total skin electron beam radiation in a pediatric patient with leukemia cutis: a case report

Leukemia cutis, a form of extramedullary leukemia involving the skin, is a poor prognostic marker and indicator of imminent hematologic relapse and chemotherapeutic resistance in leukemia patients. Although total skin electron beam radiotherapy is commonly recommended for patients with leukemia cuti...

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Bibliographic Details
Published in:	Journal of pediatric hematology/oncology Vol. 34; no. 7; pp. 556 - 558
Main Authors:	Majd, Nazanin K, Jain, Sheena K, Murphy, Mike C, Dugas, Joseph P, Hager, Frederick, Abdulrahman, Ramzi
Format:	Journal Article
Language:	English
Published:	United States 01-10-2012
Subjects:	Female Humans Infant Radiotherapy, High-Energy - methods Sarcoma, Myeloid - radiotherapy Skin Neoplasms - radiotherapy
Online Access:	Get full text
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Summary:	Leukemia cutis, a form of extramedullary leukemia involving the skin, is a poor prognostic marker and indicator of imminent hematologic relapse and chemotherapeutic resistance in leukemia patients. Although total skin electron beam radiotherapy is commonly recommended for patients with leukemia cutis, its role and effectiveness remains unclear. Here we describe a 19-month-old infant with acute myelogenous leukemia first diagnosed at 15 months of age. It relapsed in her skin at 18 months of age, associated with raised hyperpigmented lesions on her chest and scalp. Radiation treatment to the total skin surface with radiation therapy resulted in relief of her symptoms before relapse in the bone marrow.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1077-4114 1536-3678
DOI:	10.1097/MPH.0b013e3182678e9f