Early fluid resuscitation in sepsis: evidence and perspectives

Hemodynamic instability plays a major role in the pathogenesis of systemic inflammation, tissue hypoxia, and multiple organ dysfunction in sepsis. Aggressive fluid replacement is one of the key interventions for the hemodynamic support in severe sepsis. In this scenario, the ability to restore the i...

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Bibliographic Details
Published in:	Shock (Augusta, Ga.) Vol. 34 Suppl 1; no. 7; pp. 40 - 43
Main Authors:	Bozza, Fernando A, Carnevale, Renata, Japiassú, André Miguel, Castro-Faria-Neto, Hugo Caire, Angus, Derek C, Salluh, Jorge I F
Format:	Journal Article
Language:	English
Published:	United States 01-09-2010
Subjects:	Animals Blood Transfusion Cardiotonic Agents - therapeutic use Combined Modality Therapy Emergency Service, Hospital Evidence-Based Medicine Fluid Therapy Forecasting Hemodynamics Humans Isotonic Solutions - therapeutic use Meta-Analysis as Topic Microcirculation Multicenter Studies as Topic Practice Guidelines as Topic Randomized Controlled Trials as Topic Reproducibility of Results Resuscitation - methods Sepsis - drug therapy Sepsis - mortality Sepsis - physiopathology Sepsis - therapy Treatment Outcome
Online Access:	Get full text
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