Pituitary disease and anaesthesia

Transsphenoidal pituitary surgery is a relatively common procedure in the UK and patients with pituitary gland tumours comprise a significant proportion of the neurosurgical population. Patients with pituitary disease present unique anaesthetic challenges because of hormone hypersecretion, pituitary...

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Published in:Anaesthesia and intensive care medicine Vol. 24; no. 6; pp. 348 - 352
Main Authors: Rhodes, Kim, John, Robert, Luoma, Astri
Format: Journal Article
Language:English
Published: Elsevier Ltd 01-06-2023
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Abstract Transsphenoidal pituitary surgery is a relatively common procedure in the UK and patients with pituitary gland tumours comprise a significant proportion of the neurosurgical population. Patients with pituitary disease present unique anaesthetic challenges because of hormone hypersecretion, pituitary hypofunction, or tumour mass effect. Respiratory and cardiovascular sequelae of pituitary tumours also pose challenges for anaesthetists. A thorough understanding of the anatomy, physiology and pathology is required to manage these patients safely in the perioperative period. We aim to review the key principles involved in the preoperative assessment, intraoperative management, and postoperative care of these patients.
AbstractList Transsphenoidal pituitary surgery is a relatively common procedure in the UK and patients with pituitary gland tumours comprise a significant proportion of the neurosurgical population. Patients with pituitary disease present unique anaesthetic challenges because of hormone hypersecretion, pituitary hypofunction, or tumour mass effect. Respiratory and cardiovascular sequelae of pituitary tumours also pose challenges for anaesthetists. A thorough understanding of the anatomy, physiology and pathology is required to manage these patients safely in the perioperative period. We aim to review the key principles involved in the preoperative assessment, intraoperative management, and postoperative care of these patients.
Author Luoma, Astri
Rhodes, Kim
John, Robert
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10.1016/j.mpaic.2020.03.003
10.1097/01.aco.0000432521.01339.ab
10.1093/bjaceaccp/mkr014
10.3803/EnM.2022.1546
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Keywords pituitary
transsphenoidal surgery
prolactinoma
diabetes insipidus
Cushing's disease
Acromegaly
anaesthesia
Language English
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Dunn (10.1016/j.mpaic.2023.03.012_bib2) 2013; 26
Hanson (10.1016/j.mpaic.2023.03.012_bib3) 2020; 6
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SubjectTerms Acromegaly
anaesthesia
Cushing's disease
diabetes insipidus
pituitary
prolactinoma
transsphenoidal surgery
Title Pituitary disease and anaesthesia
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