Fluid and electrolyte imbalance in renal dysfunction
Kidneys have a major role in maintaining homeostasis of body fluids, electrolytes concentrations, acid–base balance, and osmolality. This role is achieved by the functional unit of the kidneys, which is the nephron, through four consequent mechanisms: filtration, reabsorption, secretion, and excreti...
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| Published in: | Anaesthesia and intensive care medicine Vol. 25; no. 5; pp. 316 - 319 |
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| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
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Elsevier Ltd
01-05-2024
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| Abstract | Kidneys have a major role in maintaining homeostasis of body fluids, electrolytes concentrations, acid–base balance, and osmolality. This role is achieved by the functional unit of the kidneys, which is the nephron, through four consequent mechanisms: filtration, reabsorption, secretion, and excretion. Additionally, kidneys synthesize two hormones – erythropoietin and renin – and participate in calcium homeostasis. It is essential to recognize and manage acute or chronic kidney dysfunction to avoid further deterioration of kidneys and electrolytes imbalance, which both can be fatal. |
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| AbstractList | Kidneys have a major role in maintaining homeostasis of body fluids, electrolytes concentrations, acid–base balance, and osmolality. This role is achieved by the functional unit of the kidneys, which is the nephron, through four consequent mechanisms: filtration, reabsorption, secretion, and excretion. Additionally, kidneys synthesize two hormones – erythropoietin and renin – and participate in calcium homeostasis. It is essential to recognize and manage acute or chronic kidney dysfunction to avoid further deterioration of kidneys and electrolytes imbalance, which both can be fatal. |
| Author | Deabes, Ahmed Abdelhamid Essa, Ahmed |
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| Cites_doi | 10.1016/j.mpaic.2021.05.008 10.1016/j.bjae.2022.03.005 10.1530/EC-16-0056 |
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| Keywords | sodium potassium renal dysfunction Calcium kidney injury electrolyte |
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| References | National Institute for Health and Care Excellence (NICE). Fluids and electrolytes. British National Formulary. Treatment Summaries. (bib5) 2015 McGregor, Jones (bib4) 2021; 22 (bib1) 2013; 1 (bib2) 2019 McLure, Chowdhury (bib3) 2022; 22 Turner, Gittoes, Selby (bib7) 2016; 5 (10.1016/j.mpaic.2024.03.006_bib2) 2019 McLure (10.1016/j.mpaic.2024.03.006_bib3) 2022; 22 McLure (10.1016/j.mpaic.2024.03.006_bib8) 2022; 22 McGregor (10.1016/j.mpaic.2024.03.006_bib4) 2021; 22 (10.1016/j.mpaic.2024.03.006_bib1) 2013; 1 (10.1016/j.mpaic.2024.03.006_bib5) 2015 10.1016/j.mpaic.2024.03.006_bib6 Turner (10.1016/j.mpaic.2024.03.006_bib7) 2016; 5 |
| References_xml | – volume: 1 year: 2013 ident: bib1 article-title: KDIGO 2012 clinical practice guideline for acute kidney injury publication-title: Kidney inter Suppl – volume: 22 start-page: 321 year: 2022 end-page: 328 ident: bib3 article-title: Chronic kidney disease and anaesthesia publication-title: BJA Educ contributor: fullname: Chowdhury – year: 2019 ident: bib2 article-title: Acute kidney injury: prevention, detection and management clinical guideline [CG148] – volume: 22 start-page: 406 year: 2021 end-page: 409 ident: bib4 article-title: Fluid and electrolyte problems in renal dysfunction publication-title: Anaesth Intensive Care Med contributor: fullname: Jones – year: 2015 ident: bib5 article-title: Guidelines for Resuscitation: 2015, Section 4. Cardiac arrest in special circumstances – volume: 5 start-page: G7 year: 2016 end-page: G8 ident: bib7 article-title: Emergency management of acute hypocalcaemia in adult patients publication-title: Endocr Connect contributor: fullname: Selby – volume: 1 year: 2013 ident: 10.1016/j.mpaic.2024.03.006_bib1 article-title: KDIGO 2012 clinical practice guideline for acute kidney injury publication-title: Kidney inter Suppl – volume: 22 start-page: 406 year: 2021 ident: 10.1016/j.mpaic.2024.03.006_bib4 article-title: Fluid and electrolyte problems in renal dysfunction publication-title: Anaesth Intensive Care Med doi: 10.1016/j.mpaic.2021.05.008 contributor: fullname: McGregor – year: 2015 ident: 10.1016/j.mpaic.2024.03.006_bib5 – volume: 22 start-page: 321 year: 2022 ident: 10.1016/j.mpaic.2024.03.006_bib8 article-title: Chronic kidney disease and anaesthesia publication-title: BJA Education doi: 10.1016/j.bjae.2022.03.005 contributor: fullname: McLure – year: 2019 ident: 10.1016/j.mpaic.2024.03.006_bib2 – ident: 10.1016/j.mpaic.2024.03.006_bib6 – volume: 5 start-page: G7 year: 2016 ident: 10.1016/j.mpaic.2024.03.006_bib7 article-title: Emergency management of acute hypocalcaemia in adult patients publication-title: Endocr Connect doi: 10.1530/EC-16-0056 contributor: fullname: Turner – volume: 22 start-page: 321 year: 2022 ident: 10.1016/j.mpaic.2024.03.006_bib3 article-title: Chronic kidney disease and anaesthesia publication-title: BJA Educ doi: 10.1016/j.bjae.2022.03.005 contributor: fullname: McLure |
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| Title | Fluid and electrolyte imbalance in renal dysfunction |
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