Identification of the MICA∗ 070 allele by sequencing and phasing

Abstract A novel MICA allele, MICA∗ 070, was defined by sequencing. The new allele differs from the MICA∗ 008:04 sequence in exon 2, encoding a C instead of G corresponding to cDNA nucleotide position 183. This nucleotide substitution is predicted to encode serine instead of arginine at residue 38 o...

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Bibliographic Details
Published in:	Human immunology Vol. 74; no. 5; pp. 557 - 561
Main Authors:	Moran, D, Morishima, S, Malkki, M, Petersdorf, E.W
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01-05-2013
Subjects:	Allergy and Immunology
Online Access:	Get full text
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Summary:	Abstract A novel MICA allele, MICA∗ 070, was defined by sequencing. The new allele differs from the MICA∗ 008:04 sequence in exon 2, encoding a C instead of G corresponding to cDNA nucleotide position 183. This nucleotide substitution is predicted to encode serine instead of arginine at residue 38 of the α1 domain of the MICA molecule.
ISSN:	0198-8859 1879-1166
DOI:	10.1016/j.humimm.2012.11.009