Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved]

Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved]

Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-rela...

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Bibliographic Details
Published in:F1000 research Vol. 12; p. 337
Main Authors: Daboussi, Selsabil, Essebaa, Samia, Mhamdi, Samira, Aichaouia, Chiraz, Hela, Ghedira, Ayadi, Aida, Zied, Moetemri
Format: Journal Article
Language:English
Published: London Faculty of 1000 Ltd 2023
Subjects:
Asthma
Biopsy
Case reports
Consent
Dyspnea
Leukocytes (eosinophilic)
Lung diseases
Patients
Pneumonia
Respiration
Steroids
Tunisia
Corticosteroid
Treatment
Idiopathic chronic eosinophilic pneumonia
Mepolizumab
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Summary:Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-relapsing and steroid-dependent ICEP was made respectively. Mepolizumab was prescribed to both patients. This treatment resulted in successful long-term disease management with much fewer side effects than a traditional corticosteroid therapy.
Bibliography:new_version
ISSN:2046-1402
2046-1402
DOI:10.12688/f1000research.130939.3