Epigenetic enzymes are the therapeutic targets for CD4+CD25+/highFoxp3+ regulatory T cells

CD4+CD25+/highFoxp3+ regulatory T (Treg) cells are a subset of CD4+ T cells that play an essential role in maintaining peripheral immune tolerance. Several transcriptional cofactors have been recently identified, which form complexes with transcription factor Foxp3 of Treg cells and contribute in th...

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Bibliographic Details
Published in:	Translational research : the journal of laboratory and clinical medicine Vol. 165; no. 1; pp. 221 - 240
Main Authors:	Lopez-Pastrana, Jahaira, Shao, Ying, Chernaya, Valeria, Wang, Hong, Yang, Xiao-Feng
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01-01-2015
Subjects:	DNMTs HDACs TSA H3S10 TSDR TIP-60 ncRNAs Mbd CGIs H2Bub1 Tr1 HAT LAP HDACi
Online Access:	Get full text
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