"Knife-cut" intertriginous ulcers related to herpes simplex virus in three patients

Linear intertriginous erosions and ulcerations related to herpes simplex virus (HSV) infection have been reported in patients with underlying immunosuppression. This rare presentation of HSV seems to occur predominantly in patients undergoing treatment of hematologic malignancies and rheumatologic c...

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Bibliographic Details
Published in:	Dermatology online journal Vol. 28; no. 4
Main Authors:	Millan, Sarah, Ali, Rowanne, Sanfilippo, Eric, Siegel, Marc, Cardis, Michael A, Saardi, Karl M
Format:	Journal Article
Language:	English
Published:	Oakland University of California Digital Library - eScholarship 30-08-2022
Subjects:	Dermatology Herpes viruses Ulcers
Online Access:	Get full text
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Summary:	Linear intertriginous erosions and ulcerations related to herpes simplex virus (HSV) infection have been reported in patients with underlying immunosuppression. This rare presentation of HSV seems to occur predominantly in patients undergoing treatment of hematologic malignancies and rheumatologic conditions. Herein, we report three cases of linear "knife-cut" ulcerations in patients who were not undergoing active pharmacologic immunosuppressive therapy and lacked coexisting malignancy or autoimmune disease. Close examination of the skin folds for HSV infection is warranted to rule out disseminated infection as early intervention can be lifesaving.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1087-2108 1087-2108
DOI:	10.5070/D328458529