Activation of CD8+ murine T cells from tumor-draining lymph nodes by phorbol dibutyrate plus calcium ionophore

When lymphocytes from the lymph nodes draining the site of a progressively growing MCA-105 sarcoma are stimulated in vitro with autologous tumor and low-dose interleukin-2 (IL-2), they will grow and develop the ability to lyse autologous tumor cells in vitro; these lymphocytes can also eradicate tum...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of immunotherapy Vol. 12; no. 1; p. 32
Main Authors:	Tuttle, T M, Inge, T H, McCrady, C M, Bethke, K P, Bear, H D
Format:	Journal Article
Language:	English
Published:	United States 01-07-1992
Subjects:	Animals Cells, Cultured Cytotoxicity Tests, Immunologic Female Immunophenotyping Immunotherapy, Adoptive Ionomycin - pharmacology Lymph Nodes - immunology Lymph Nodes - pathology Lymphocyte Activation - drug effects Lymphocyte Depletion Mice Mice, Inbred C57BL Phorbol 12,13-Dibutyrate - pharmacology Remission Induction - methods Sarcoma, Experimental - chemically induced Sarcoma, Experimental - drug therapy Sarcoma, Experimental - immunology Sarcoma, Experimental - pathology T-Lymphocytes, Regulatory - drug effects Time Factors
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!