Deoxyfluorination with superacids - synthesis and characterization of protonated α-fluorohydroxyacetic acid

α-Fluoroalcohols describe a rare and unstable class of compounds, accessible mainly by fluorination of highly electrophilic carbonyl compounds. In this work, we report the syntheses of α-fluorohydroxyacetic acid (FHA) and its acyl fluoride (FHA-F) by reacting the dihydroxy species glyoxylic acid mon...

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Bibliographic Details

Published in:	RSC advances Vol. 14; no. 43; pp. 31517 - 31523
Main Authors:	Virmani, Alan, Jessen, Christoph, Nitzer, Alexander, Kornath, Andreas J
Format:	Journal Article
Language:	English
Published:	England Royal Society of Chemistry 01-10-2024
Subjects:	Carbonyl compounds Carbonyls Fluorination Glyoxylic acid NMR Nuclear magnetic resonance Single crystals
Online Access:	Get full text
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