Unraveling clinical outcomes of long-term cART treatment in HIV-1 patients with or without the Brazilian GWGR motif in the V3 loop

The presence of genetic mutations in HIV poses a significant challenge, potentially leading to antiretroviral resistance and hampering therapeutic development. The Brazilian population has presented variations in the HIV envelope V3 loop gene, especially the GWGR motif. This motif has been linked to...

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Bibliographic Details
Published in:	Revista do Instituto de Medicina Tropical de São Paulo Vol. 66; p. e38
Main Authors:	Folgosi, Victor Ângelo, Komninakis, Shirley Vasconcelos, Lopes, Luciano, Monteiro, Mariana Amélia, Assone, Tatiane, Fonseca, Luiz Augusto Marcondes, Domingues, Wilson, Leite Junior, Pedro Domingos, Victor, Jefferson Russo, Casseb, Jorge
Format:	Journal Article
Language:	English
Published:	Brazil Instituto de Medicina Tropical de São Paulo 2024
Subjects:	Adult Amino Acid Motifs Anti-HIV Agents - therapeutic use Antiretroviral Therapy, Highly Active Brazil CD4 Lymphocyte Count Cohort Studies Disease Progression Female HIV Envelope Protein gp120 - genetics HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects HIV-1 - genetics Humans Male Middle Aged Mutation Original Treatment Outcome TROPICAL MEDICINE Viral Load Brazil HIV-1 GWGR signature Brazil ART Subtype B
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