1, 8-Naphthalimide-based fluorescent sensor with highly selective and sensitive detection of Zn2+ in aqueous solution and living cells
A new 4-amino-1, 8-naphthalimide-based fluorescent sensor, with iminoethoxyacetic acid and iminopicolinic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with...
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Published in: | Inorganic chemistry communications Vol. 106; pp. 43 - 47 |
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Elsevier B.V
01-08-2019
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Abstract | A new 4-amino-1, 8-naphthalimide-based fluorescent sensor, with iminoethoxyacetic acid and iminopicolinic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with about 30-fold enhancement in aqueous solution, with a characteristic emission band of 4-amino-1,8-naphthalimide with a green color centered at 550 nm.
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•1, 8-Naphthalimide-based fluorescent Zn2+ sensor with a new receptor contained two different arms was synthesized.•It demonstrates high selectivity and sensitivity for sensing Zn2+ with about 41-fold enhancement.•It was applied successfully to detection of Zn2+ in aqueous solution and image Zn2+ in living cells. |
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AbstractList | A new 4-amino-1, 8-naphthalimide-based fluorescent sensor, with iminoethoxyacetic acid and iminopicolinic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with about 30-fold enhancement in aqueous solution, with a characteristic emission band of 4-amino-1,8-naphthalimide with a green color centered at 550 nm.
[Display omitted]
•1, 8-Naphthalimide-based fluorescent Zn2+ sensor with a new receptor contained two different arms was synthesized.•It demonstrates high selectivity and sensitivity for sensing Zn2+ with about 41-fold enhancement.•It was applied successfully to detection of Zn2+ in aqueous solution and image Zn2+ in living cells. |
Author | Shang, Zhiqiang Yang, Guangming Zhu, Hualing Shi, Jun Chen, Jiatong Yin, Xin Deng, Xinxin Liu, Daying He, Huarui |
Author_xml | – sequence: 1 givenname: Daying surname: Liu fullname: Liu, Daying email: dyxyliu@mail.nankai.edu.cn organization: College of Basic Science, Chemistry Experiment Teaching Center, Tianjin Agricultural University, Tianjin, China – sequence: 2 givenname: Xin surname: Yin fullname: Yin, Xin organization: College of Basic Science, Chemistry Experiment Teaching Center, Tianjin Agricultural University, Tianjin, China – sequence: 3 givenname: Xinxin surname: Deng fullname: Deng, Xinxin organization: College of Basic Science, Chemistry Experiment Teaching Center, Tianjin Agricultural University, Tianjin, China – sequence: 4 givenname: Jun surname: Shi fullname: Shi, Jun organization: College of Basic Science, Chemistry Experiment Teaching Center, Tianjin Agricultural University, Tianjin, China – sequence: 5 givenname: Hualing surname: Zhu fullname: Zhu, Hualing organization: College of Basic Science, Chemistry Experiment Teaching Center, Tianjin Agricultural University, Tianjin, China – sequence: 6 givenname: Zhiqiang surname: Shang fullname: Shang, Zhiqiang organization: College of Basic Science, Chemistry Experiment Teaching Center, Tianjin Agricultural University, Tianjin, China – sequence: 7 givenname: Jiatong surname: Chen fullname: Chen, Jiatong organization: Department of Chemistry, Department of Biochemistry and Molecular Biology, Key Laboratory of Advanced Energy Materials Chemistry, Ministry of Education, Nankai University, Tianjin, China – sequence: 8 givenname: Guangming surname: Yang fullname: Yang, Guangming organization: Department of Chemistry, Department of Biochemistry and Molecular Biology, Key Laboratory of Advanced Energy Materials Chemistry, Ministry of Education, Nankai University, Tianjin, China – sequence: 9 givenname: Huarui surname: He fullname: He, Huarui email: huarui.he@heowns.com organization: Heowns Biochem Technologies LLC, Tianjin, China |
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Keywords | Iminoethoxyacetic acid Fluorescent sensor Naphthalimide Iminopicolinic acid Zinc |
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SubjectTerms | Fluorescent sensor Iminoethoxyacetic acid Iminopicolinic acid Naphthalimide Zinc |
Title | 1, 8-Naphthalimide-based fluorescent sensor with highly selective and sensitive detection of Zn2+ in aqueous solution and living cells |
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