1, 8-Naphthalimide-based fluorescent sensor with highly selective and sensitive detection of Zn2+ in aqueous solution and living cells

A new 4-amino-1, 8-naphthalimide-based fluorescent sensor, with iminoethoxyacetic acid and iminopicolinic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with...

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Published in:Inorganic chemistry communications Vol. 106; pp. 43 - 47
Main Authors: Liu, Daying, Yin, Xin, Deng, Xinxin, Shi, Jun, Zhu, Hualing, Shang, Zhiqiang, Chen, Jiatong, Yang, Guangming, He, Huarui
Format: Journal Article
Language:English
Published: Elsevier B.V 01-08-2019
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Abstract A new 4-amino-1, 8-naphthalimide-based fluorescent sensor, with iminoethoxyacetic acid and iminopicolinic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with about 30-fold enhancement in aqueous solution, with a characteristic emission band of 4-amino-1,8-naphthalimide with a green color centered at 550 nm. [Display omitted] •1, 8-Naphthalimide-based fluorescent Zn2+ sensor with a new receptor contained two different arms was synthesized.•It demonstrates high selectivity and sensitivity for sensing Zn2+ with about 41-fold enhancement.•It was applied successfully to detection of Zn2+ in aqueous solution and image Zn2+ in living cells.
AbstractList A new 4-amino-1, 8-naphthalimide-based fluorescent sensor, with iminoethoxyacetic acid and iminopicolinic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with about 30-fold enhancement in aqueous solution, with a characteristic emission band of 4-amino-1,8-naphthalimide with a green color centered at 550 nm. [Display omitted] •1, 8-Naphthalimide-based fluorescent Zn2+ sensor with a new receptor contained two different arms was synthesized.•It demonstrates high selectivity and sensitivity for sensing Zn2+ with about 41-fold enhancement.•It was applied successfully to detection of Zn2+ in aqueous solution and image Zn2+ in living cells.
Author Shang, Zhiqiang
Yang, Guangming
Zhu, Hualing
Shi, Jun
Chen, Jiatong
Yin, Xin
Deng, Xinxin
Liu, Daying
He, Huarui
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Keywords Iminoethoxyacetic acid
Fluorescent sensor
Naphthalimide
Iminopicolinic acid
Zinc
Language English
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Snippet A new 4-amino-1, 8-naphthalimide-based fluorescent sensor, with iminoethoxyacetic acid and iminopicolinic acid as receptor, was developed and applied...
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SubjectTerms Fluorescent sensor
Iminoethoxyacetic acid
Iminopicolinic acid
Naphthalimide
Zinc
Title 1, 8-Naphthalimide-based fluorescent sensor with highly selective and sensitive detection of Zn2+ in aqueous solution and living cells
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