CENTRAL PULSE PRESSURE AND ITS HEMODYNAMIC DETERMINANTS IN MIDDLE-AGED ADULTS WITH IMPAIRED FASTING GLUCOSE AND DIABETES MELLITUS: THE ASKLEPIOS STUDY

• Published in: Journal of the American College of Cardiology Vol. 61; no. 10; p. E1446
• Main Authors: Chirinos, Julio A, Segers, Patrick, Gillebert, Thierry C, De Buyzere, Marc, Van daele, Caroline M, Khan, Zubair A, Khawar, Muhammad U, De Bacquer, Dirk, Rietzschel, Ernst R
• Format: Journal Article
• Language: English
• Published: New York Elsevier Inc 12-03-2013; Elsevier Limited
• Subjects: Cardiology; Cardiovascular; Diabetes; Fasting; Hyperglycemia; Internal Medicine
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/S0735-1097(13)61446-1

Normal FG (n=1654) Impaired FG (n=240) type-2 diabetes (n=33) P value Total arterial compliance, mmHg.mL.m-2 1.02 (1.01-1.03) 1.01 (0.98-1.04) 0.89 (0.8-0.97) 0.012 [dagger][double dagger] Aortic characteristic impedance, mmHg·ms·mL-1·m1.3 0.12 (0.12-0.13) 0.12 (0.12-0.13) 0.14 (0.13-0.15) 0.052 Ascending aortic Eh (kdyne/cm) 285 (275-296) 283 (256-312) 402 (309-523) 0.038 [dagger][double dagger] Carotid-Femoral PWV (m/s) 6.6 (6.54-6.65) 6.57 (6.43-6.71) 7.34 (6.96-7.73) 0.001 [dagger][double dagger] Reflected wave transit time (msec) 63 (62-64) 64 (62-66) 63 (58-69) 0.95 Reflection Magnitude 0.48 (0.48-0.48) 0.48 (0.47-0.48) 0.43 (0.4-0.46) 0.002 [dagger][double dagger] [dagger] FG.