Importance of GLUT1 in differential diagnosis of vascular anomalies

• Published in: Jornal vascular brasileiro Vol. 14; no. 2; pp. 168 - 176
• Main Authors: Silva Filho, Tiago João da, Oliveira, Denise Hélen Imaculada Pereira de, Moura, Ilnara de Souza, Medeiros, Layssa Karolinne da Silva, Gonzaga, Amanda Katarinny Goes, Brasil, Veruska Lima Moura, Queiroz, Lélia Maria Guedes
• Format: Journal Article
• Language: English
• Published: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 01-06-2015
• Subjects: CARDIAC & CARDIOVASCULAR SYSTEMS; diagnóstico diferencial; hemangioma; más formações vasculares; PERIPHERAL VASCULAR DISEASE; SURGERY; hemangioma; vascular malformations; más formações vasculares; diagnosis differential; diagnóstico diferencial
• ISSN: 1677-7301; 1677-7301
• DOI: 10.1590/1677-5449.0069

Vascular anomalies (VAs) include a group of distinct lesions, such as vascular system congenital malformations, as well as benign and malignant vascular tumors. These lesions may present similar clinical and histopathological features, leading to mistaken diagnoses and incorrect treatment choices. It is important that professionals responsible for monitoring the development of VAs conduct precise investigations and use the appropriate terminology. The human glucose transporter protein isoform 1 (GLUT1) has been proposed as a tool to aid in differential diagnosis between different VAs, given that it is a sensitive and specific marker for identification of infantile hemangiomas (HIs) in any organ. This article presents a review of the literature on this protein as an effective tool for identification and possible differential diagnosis between several VAs.