Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis

• Published in: Tuberkulëz i bolezni lëgkikh Vol. 100; no. 6; pp. 53 - 58
• Main Authors: Zhukova, E. M., Kulchavenya, E. V.
• Format: Journal Article
• Language: English
• Published: New Terra Publishing House 13-07-2022
• Subjects: вич-инфекция; множественная лекарственная устойчивость; рак почки; туберкулез; химиотерапия
• ISSN: 2075-1230; 2542-1506
• DOI: 10.21292/2075-1230-2022-100-6-53-58

The article describes a clinical observation of the effective treatment of a multimorbid HIV positive patient with multiple drug resistant tuberculosis. It demonstrates modern approaches to treatment and optimal chemotherapy regimens containing bedaquiline. In the treatment of patients with a combination of chronic infectious diseases (tuberculosis, HIV infection, parenteral hepatitis) and oncological pathology (kidney cancer), interdepartmental interaction of specialists (phthisiologists, infectious disease specialists, and oncologists) is needed in order to compile successful treatment regimens taking into account multiple comorbidities and the risk of adverse reactions to drug combinations and choose the right time to perform a successful surgery.