IgG Antibody Interference Diminishes Accuracy of Chip-Based Allergen-specific IgE Assays

[...]the chip-based ISAC (using more limited casein-allergen binding sites) displayed IgG anti-casein dose-dependent increases up to 991% in the quantity of detected IgE anti-casein following removal of IgG anti-casein.

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Bibliographic Details
Published in:	Journal of allergy and clinical immunology Vol. 125; no. 2; p. AB223
Main Author:	Hamilton, R.G
Format:	Journal Article
Language:	English
Published:	St. Louis Mosby, Inc 01-02-2010 Elsevier Limited
Subjects:	Accuracy Allergies Allergy and Immunology
Online Access:	Get full text
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Description
Summary:	[...]the chip-based ISAC (using more limited casein-allergen binding sites) displayed IgG anti-casein dose-dependent increases up to 991% in the quantity of detected IgE anti-casein following removal of IgG anti-casein.
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2009.12.872