PET-Train: Automatic Ground Truth Generation from PET Acquisitions for Urinary Bladder Segmentation in CT Images using Deep Learning

• Published in: 2018 11th Biomedical Engineering International Conference (BMEiCON) pp. 1 - 5
• Main Authors: Gsaxner, Christina, Pfarrkirchner, Birgit, Lindner, Lydia, Pepe, Antonio, Roth, Peter M., Egger, Jan, Wallner, Jurgen
• Format: Conference Proceeding
• Language: English
• Published: IEEE 01-11-2018
• Subjects: Bladder; Computed tomography; Deep learning; Image segmentation; Medical Imaging; Neural networks; PET/CT; Positron emission tomography; Segmentation; Training; Urinary Bladder
• DOI: 10.1109/BMEiCON.2018.8609954

In this contribution, we propose an automatic ground truth generation approach that utilizes Positron Emission Tomography (PET) acquisitions to train neural networks for automatic urinary bladder segmentation in Computed Tomography (CT) images. We evaluated different deep learning architectures to segment the urinary bladder. However, deep neural networks require a large amount of training data, which is currently the main bottleneck in the medical field, because ground truth labels have to be created by medical experts on a time-consuming slice-by-slice basis. To overcome this problem, we generate the training data set from the PET data of combined PET/CT acquisitions. This can be achieved by applying simple thresholding to the PET data, where the radiotracer accumulates very distinct in the urinary bladder. However, the ultimate goal is to entirely skip PET imaging and its additional radiation exposure in the future, and only use CT images for segmentation.