Two New Scalaranes from a Korean Marine Sponge Spongia sp

Intensive chemical investigation of Korean marine sponge Spongia sp. has led to the isolation of two new scalaranes. The planar structures of the new compounds 1 and 2 were determined through 1D and 2D NMR spectral data analysis, while the relative stereochemistry of the compounds was determined bas...

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Bibliographic Details
Published in:	Natural product sciences Vol. 21; no. 4; pp. 289 - 292
Main Authors:	Yang, Inho, Nam, Sang-Jip, Kang, Heonjoong
Format:	Journal Article
Language:	English
Published:	한국생약학회 2015
Subjects:	약학 Sesterpenoid Korean sponge Scalarane Marine natural product Spongia sp
Online Access:	Get full text
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Summary:	Intensive chemical investigation of Korean marine sponge Spongia sp. has led to the isolation of two new scalaranes. The planar structures of the new compounds 1 and 2 were determined through 1D and 2D NMR spectral data analysis, while the relative stereochemistry of the compounds was determined based on the analysis of 1H-1H coupling constants and NOESY spectroscopic data. Compounds 1 and 2 did not display any significant biological activities on farnesoid X-activated receptor (FXR) in co-transfection assay. KCI Citation Count: 0
Bibliography:	G704-001403.2015.21.4.006
ISSN:	1226-3907 2288-9027
DOI:	10.20307/nps.2015.21.4.289