Down-regulation of liver Gal β1, 4GlcNAc α2, 6-sialyltransferase gene by ethanol significantly correlates with alcoholic steatosis in humans

Hepatic steatosis and steatohepatitis are frequent results of long-term ethanol exposure. We have previously demonstrated that long-term ethanol down-regulates Gal βl, 4GlcNAc α2, 6-sialyltransferase (ST6Gal1), leading to defective glycosylation of a number of proteins including apolipoprotein (apo)...

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Bibliographic Details

Published in:	Metabolism, clinical and experimental Vol. 57; no. 12; pp. 1663 - 1668
Main Authors:	Gong, Maokai, Castillo, Leslie, Redman, Robert S., Garige, Mamatha, Hirsch, Kenneth, Azuine, Magnus, Amdur, Richard L., Seth, Devanshi, Haber, Paul S., Lakshman, M. Raj
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01-12-2008
Online Access:	Get full text
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