GRANULOMATOSIS WITH POLYANGIITIS (GPA) PRESENTING WITH FROSTED BRANCH ANGIITIS

• Published in: Retinal cases & brief reports Vol. 10; no. 3; pp. 249 - 251
• Main Authors: Sandhu, Rasanamar K, Adams, Tony, Sibley, Cailin, Suhler, Eric B, Kim, Donna H
• Format: Journal Article
• Language: English
• Published: United States 2016
• Subjects: Acute Disease; Blindness - etiology; Female; Granulomatosis with Polyangiitis - complications; Humans; Retinal Vasculitis - etiology; Young Adult
• ISSN: 1935-1089; 1937-1578
• DOI: 10.1097/ICB.0000000000000242

To report a case of frosted branch angiitis in a patient with granulomatosis with polyangiitis.
Clinical case report. Imaging was obtained with pseudo-color scanning laser ophthalmoscope photographs, fluorescein angiography, spectral domain optical coherence tomography, and B-scan ultrasound.
A 24-year-old woman with a clinical history of granulomatosis with polyangiitis who presented with acute vision loss was found to have frosted branch angiitis with concurrent posterior scleritis and orbital inflammation. These findings improved rapidly after initiation of high-dose intravenous solumedrol.
This is a unique case of frosted branch angiitis associated with granulomatosis with polyangiitis. The authors are not aware of a previous report of this association. Although rare, retinal vasculitis should be recognized as a potential complication of granulomatosis with polyangiitis and can respond rapidly to prompt initiation of therapy.