Identification of G protein-coupled, inward rectifier potassium channel gene products from the rat anterior pituitary gland

Dopamine (DA) is a physiological regulator of PRL secretion, exerting tonic inhibitory control. DA activates an inward rectifier K(+) (IRK) channel in rat lactotropes, causing membrane hyperpolarization and inhibition of Ca(2+)-dependent action potentials. Both the activation of this effector K(+) c...

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Bibliographic Details
Published in:	Endocrinology (Philadelphia) Vol. 142; no. 7; pp. 2820 - 2832
Main Authors:	Gregerson, K A, Flagg, T P, O'Neill, T J, Anderson, M, Lauring, O, Horel, J S, Welling, P A
Format:	Journal Article
Language:	English
Published:	United States 01-07-2001
Subjects:	Animals Blotting, Northern Electric Conductivity Female G Protein-Coupled Inwardly-Rectifying Potassium Channels Kinetics Oocytes Pituitary Gland, Anterior - metabolism Potassium Channels - metabolism Potassium Channels - physiology Potassium Channels, Inwardly Rectifying Precipitin Tests Rats Rats, Sprague-Dawley Receptors, Dopamine D2 - physiology Reverse Transcriptase Polymerase Chain Reaction Xenopus laevis
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