Effects of microiontophoretically injected AMP and cAMP on calcium current in dialyzed Helix pomatia neurons

Effects of microiontophoretically injected AMP and cAMP on calcium current in dialyzed Helix pomatia neurons

The effects of injecting cells with adenosine monophosphate (AMP) and cyclic adenosine monophosphate (cAMP) on calcium current were investigated during intracellular dialysis of Helix pomatia neurons. Microiontophoretically injected AMP was found to lead to reinstatement of calcium current following...

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Bibliographic Details
Published in:Neurophysiology (New York) Vol. 20; no. 6; pp. 559 - 564
Main Authors: Kononenko, N. I., Shcherbatko, A. D.
Format: Journal Article
Language:English
Published: 01-11-1988
Subjects:
Helix pomatia
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Summary:The effects of injecting cells with adenosine monophosphate (AMP) and cyclic adenosine monophosphate (cAMP) on calcium current were investigated during intracellular dialysis of Helix pomatia neurons. Microiontophoretically injected AMP was found to lead to reinstatement of calcium current following dialysis-induced "wash-out," as well as considerable stabilization of this current with the extracellular medium at normal pH. Current-voltage relationship of the current would then undergo a 10 mV shift towards depolarization values.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0090-2977
1573-9007
DOI:10.1007/BF02150259