Efectos cardiometabólicos de la pérdida de peso
La prevalencia de sobrepeso y obesidad y, en consecuencia, de las comorbilidades relacionadas, está incrementándose de forma muy significativa a nivel mundial. Las guías recomiendan pérdidas de peso de >5% para lograr efectos beneficiosos en las distintas comorbilidades metabólicas asociadas con...
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| Published in: | Atención primaria Vol. 56; no. 10; p. 102953 |
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| Format: | Journal Article |
| Language: | Spanish |
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Elsevier España S.L.U
01-10-2024
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| Abstract | La prevalencia de sobrepeso y obesidad y, en consecuencia, de las comorbilidades relacionadas, está incrementándose de forma muy significativa a nivel mundial. Las guías recomiendan pérdidas de peso de >5% para lograr efectos beneficiosos en las distintas comorbilidades metabólicas asociadas con la obesidad. Además, pérdidas de peso mayores (>10%) producen mejorías más significativas, pudiendo incluso producir la remisión de algunas comorbilidades. En este capítulo, se revisa la evidencia del efecto de la pérdida de peso mediante distintas estrategias (cambios en estilo de vida, tratamiento farmacológico o cirugía bariátrica) sobre las principales enfermedades cardiometabólicas asociadas al exceso de tejido adiposo (diabetes tipo 2, hipertensión arterial, dislipemia, enfermedad hepática metabólica, inflamación, enfermedades cardiovasculares y mortalidad).
The prevalence of overweight and obesity, and, consequently, associated comorbidities, is increasing significantly worldwide. The guidelines recommend a percentage of weight loss> 5% to achieve beneficial effects on metabolic comorbidities associated with obesity. Furthermore, greater weight losses (> 10%) produce more significant improvements, and may even produce remission of some of these comorbidities. In this chapter, we review the evidence of the effect of weight loss through different strategies (lifestyle intervention, pharmacological treatment, or bariatric surgery) on the main cardiometabolic pathologies associated with excess adipose tissue (type 2 diabetes, high blood pressure, dyslipidemia, metabolic dysfunction-associated steatotic liver disease, inflammation, cardiovascular diseases, and mortality). |
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| AbstractList | La prevalencia de sobrepeso y obesidad y, en consecuencia, de las comorbilidades relacionadas, está incrementándose de forma muy significativa a nivel mundial. Las guías recomiendan pérdidas de peso de >5% para lograr efectos beneficiosos en las distintas comorbilidades metabólicas asociadas con la obesidad. Además, pérdidas de peso mayores (>10%) producen mejorías más significativas, pudiendo incluso producir la remisión de algunas comorbilidades. En este capítulo, se revisa la evidencia del efecto de la pérdida de peso mediante distintas estrategias (cambios en estilo de vida, tratamiento farmacológico o cirugía bariátrica) sobre las principales enfermedades cardiometabólicas asociadas al exceso de tejido adiposo (diabetes tipo 2, hipertensión arterial, dislipemia, enfermedad hepática metabólica, inflamación, enfermedades cardiovasculares y mortalidad).
The prevalence of overweight and obesity, and, consequently, associated comorbidities, is increasing significantly worldwide. The guidelines recommend a percentage of weight loss> 5% to achieve beneficial effects on metabolic comorbidities associated with obesity. Furthermore, greater weight losses (> 10%) produce more significant improvements, and may even produce remission of some of these comorbidities. In this chapter, we review the evidence of the effect of weight loss through different strategies (lifestyle intervention, pharmacological treatment, or bariatric surgery) on the main cardiometabolic pathologies associated with excess adipose tissue (type 2 diabetes, high blood pressure, dyslipidemia, metabolic dysfunction-associated steatotic liver disease, inflammation, cardiovascular diseases, and mortality). La prevalencia de sobrepeso y obesidad y, en consecuencia, de las comorbilidades relacionadas, está incrementándose de forma muy significativa a nivel mundial. Las guías recomiendan pérdidas de peso de > 5% para lograr efectos beneficiosos en las distintas comorbilidades metabólicas asociadas con la obesidad. Además, pérdidas de peso mayores (> 10%) producen mejorías más significativas, pudiendo incluso producir la remisión de algunas comorbilidades. En este capítulo, se revisa la evidencia del efecto de la pérdida de peso mediante distintas estrategias (cambios en estilo de vida, tratamiento farmacológico o cirugía bariátrica) sobre las principales enfermedades cardiometabólicas asociadas al exceso de tejido adiposo (diabetes tipo 2, hipertensión arterial, dislipemia, enfermedad hepática metabólica, inflamación, enfermedades cardiovasculares y mortalidad). Resumen: La prevalencia de sobrepeso y obesidad y, en consecuencia, de las comorbilidades relacionadas, está incrementándose de forma muy significativa a nivel mundial. Las guías recomiendan pérdidas de peso de > 5% para lograr efectos beneficiosos en las distintas comorbilidades metabólicas asociadas con la obesidad. Además, pérdidas de peso mayores (> 10%) producen mejorías más significativas, pudiendo incluso producir la remisión de algunas comorbilidades. En este capítulo, se revisa la evidencia del efecto de la pérdida de peso mediante distintas estrategias (cambios en estilo de vida, tratamiento farmacológico o cirugía bariátrica) sobre las principales enfermedades cardiometabólicas asociadas al exceso de tejido adiposo (diabetes tipo 2, hipertensión arterial, dislipemia, enfermedad hepática metabólica, inflamación, enfermedades cardiovasculares y mortalidad). Abstract: The prevalence of overweight and obesity, and, consequently, associated comorbidities, is increasing significantly worldwide. The guidelines recommend a percentage of weight loss > 5% to achieve beneficial effects on metabolic comorbidities associated with obesity. Furthermore, greater weight losses (> 10%) produce more significant improvements, and may even produce remission of some of these comorbidities. In this chapter, we review the evidence of the effect of weight loss through different strategies (lifestyle intervention, pharmacological treatment, or bariatric surgery) on the main cardiometabolic pathologies associated with excess adipose tissue (type 2 diabetes, high blood pressure, dyslipidemia, metabolic dysfunction-associated steatotic liver disease, inflammation, cardiovascular diseases, and mortality). |
| ArticleNumber | 102953 |
| Author | Sardà, Helena Pérez, Antonio Genua, Idoia |
| Author_xml | – sequence: 1 givenname: Idoia surname: Genua fullname: Genua, Idoia organization: Servicio de Endocrinología y Nutrición, Hospital de la Santa Creu i Sant Pau, Barcelona, España – sequence: 2 givenname: Helena surname: Sardà fullname: Sardà, Helena organization: Servicio de Endocrinología y Nutrición, Hospital de la Santa Creu i Sant Pau, Barcelona, España – sequence: 3 givenname: Antonio surname: Pérez fullname: Pérez, Antonio email: aperez@santpau.cat organization: Servicio de Endocrinología y Nutrición, Hospital de la Santa Creu i Sant Pau, Barcelona, España |
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| Issue | 10 |
| Keywords | Obesidad Inflamación Obesity IM Dislipemia Weight loss Dyslipidemia DM Inflammation CV HTA ACV Cardiovascular risk factors Factores de riesgo cardiovascular Pérdida de peso EHmet ECV arGLP1 IC Diabetes FA IMC |
| Language | Spanish |
| License | This is an open access article under the CC BY-NC-ND license. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
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| Notes | Estos autores han contribuido por igual en este trabajo. |
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| SubjectTerms | Cardiovascular risk factors Diabetes Dislipemia Dyslipidemia Factores de riesgo cardiovascular Inflamación Inflammation Obesidad Obesity Original Pérdida de peso Weight loss |
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| Title | Efectos cardiometabólicos de la pérdida de peso |
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