Evaluation of Roseola Infantum Cases in Terms of Demographic Properties and Laboratory Values

• Published in: Çocuk enfeksiyon dergisi Vol. 11; no. 2; pp. 53 - 59
• Main Authors: Bıçakçı, Zafer, Arvas, Muhammet Hafit, Biçer, Canozan, Akay, Ahsen, Üstebay, Sefer, Ülker Üstebay, Döndü
• Format: Journal Article
• Language: English
• Published: Istanbul Aves Yayincilik Ltd. STI 01-06-2017
• Subjects: Age; Cell culture; Cytokines; Fever; Health risk assessment; Infections; Laboratories; Neutropenia; Neutrophils; Pediatrics; Proteins; Tumor necrosis factor-TNF; Viral infections
• ISSN: 1307-1068; 1308-5271
• DOI: 10.5578/ced.201717

Objective: To share our experince from demographic and labaratory results of 46 patients who applied to our policlinic with complaints of fever and rash and diagnosed as roseola infantum between 2012-2016.Material and Methods: Labaratory and demographic findings of 41 patients who diagnosed as roseola infantum clinically had been evaluated. Roseala infantum cases were diagnosed as 10 mo old infant with high temperature over three days and nontoxic maculopapuller rash on the trunk and after making differential diagnosis of other diseases that courses with skin rash and high body temperature. Neutrophil counts between 0-500, 500-1000 and 1000-1500 were accepted as high, medium and low, respectively.Results: 25 of the patients were female (54.3%), 21 of them were male (45.7%), mean age was 11.5 ± 7.02 (3-36 months) and peak age of onset was 9-11 months. 76% of patients were (35/46) under one years of age. Disease was seen all year round but it was seen least at September and October and was seen mostly at December. Mean labaratory leves were found as: Hb 11.8 ± 0.97 g/L, HCT 35.0% ± 3.2, MCV 73.7 ± 5.10 fL, platelet count 299 ± 128.8 x 109/L, leukocyte count 7.6 ± 2.8 x 109/L, neutrophil count 1.7 ± 1.30 x 109/L, lymphocyte count 5.0 ± 2.2 x 109/L, mean C-reactive protein 4.0 ± 4.5 mg/L, AST 50 ± 14.8 U/L, ALT 24 ± 10.7 U/L, LDH 385 ± 96.6 U/L. 57.5% of the patients had neutropenia (10% severe, 35% moderate and 12.5% mild) and neutropenia resolved in one months. Mean lymphocyte/neutrophil rate was calculated as 2.94 (relative lymphocytosis). None of the patients experienced infections secondary to neutropenia and febrile convulsion.Conclusion: Under three years of age children (especially young infants) with fever without source accompanying neutropenia, relative lymphocytosis, mild AST elevation and negative CRP roseola infantum should be considered as an etiological factor.