Use of a Single Oral Dose of Doxycycline Monohydrate for Treating Gonorrheal Urethritis in Men

Use of a Single Oral Dose of Doxycycline Monohydrate for Treating Gonorrheal Urethritis in Men

A single oral dose of 250 mg. of doxycycline monohydrate produced a cure rate of 95.3 percent in 169 males with uncomplicated gonorrheal urethritis treated at the Fulton County Health Department, Atlanta, Ga. Of the 158 patients who returned for followup 96 hours after initial treatment, six had pos...

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Bibliographic Details
Published in:Public health reports (1896) Vol. 84; no. 2; pp. 182 - 183
Main Authors: Domescik, Gerald, McLone, David G., Scotti, Angelo, Mackey, Dan M.
Format: Journal Article
Language:English
Published: United States Public Health Service 01-01-1969
Subjects:
Dosage
Medical treatment failures
Public health
Single status
Urethritis
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Summary:A single oral dose of 250 mg. of doxycycline monohydrate produced a cure rate of 95.3 percent in 169 males with uncomplicated gonorrheal urethritis treated at the Fulton County Health Department, Atlanta, Ga. Of the 158 patients who returned for followup 96 hours after initial treatment, six had positive cultures and were considered treatment failures. Two of the 11 patients who returned to the clinic 1 to 2 weeks after their condition was diagnosed and treated had positive cultures, and their cases were considered reinfections. Only one incident of gastrointestinal intolerance characterized by vomiting occurred. No other adverse side effects were noted. No statistically significant relationships between age, race, number of previous infections, or duration of symptoms and treatment failure were found.
ISSN:0094-6214
2327-6258
DOI:10.2307/4593535