Protective Effects of Vitamin C Nanoparticles Supplemented Diet against Toxicity of Fe2+ and Mn2+ Mixture on Nile Tilapia; Oreochromis niloticus

The current study examines the effects of vitamin C nanoparticles on fish health as well as the acute and long-term toxic effects of Fe2+ and Mn2+ combination on Nile tilapia, Oreochromis niloticus. The metal mixture under study has a detected 96-hour LC50 of 2.7% TU (Toxic unit). Fish were divided...

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Published in:	Journal of Water and Environment Technology Vol. 22; no. 5; pp. 232 - 240
Main Authors:	Abd-elrahman, Hatem H., Aly, Mohamed Y. M., Eldesouky, Mahmoud Rasly, Flefel, Hassan E.
Format:	Journal Article
Language:	English
Published:	Japan Society on Water Environment 2024
Subjects:	Metals Oreochromis niloticus remediation toxicity vitamin C nanoparticles
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Abstract	The current study examines the effects of vitamin C nanoparticles on fish health as well as the acute and long-term toxic effects of Fe2+ and Mn2+ combination on Nile tilapia, Oreochromis niloticus. The metal mixture under study has a detected 96-hour LC50 of 2.7% TU (Toxic unit). Fish were divided into four groups: Group 1, which served as the control group; Groups 2, 3, and 4 were exposed to 20% of the 96-hour LC50 for 30 days and fed on a conventional diet. Fish of Group 3 were supplemented with 20% vitamin C while fish of Group 4 were supplemented with 20% vitamin C as nanoparticles. The metals, levels in tissues of the liver and gills were examined, as well as the biochemical markers of metabolic processes in blood plasma. Fish from Group 2 displayed noticeable deteriorating conditions, followed by those from Group 3, whereas fish from Group 4 demonstrated noticeable good conditions across all examined criteria. Results showed that, while vitamin C nanoparticle proved to be more efficient, both vitamin C and its nanoparticles supplements had a positive impact on reducing the harmful effects of the studied metal mixture by chelating metal ions and scavenging free radicals.
AbstractList	The current study examines the effects of vitamin C nanoparticles on fish health as well as the acute and long-term toxic effects of Fe2+ and Mn2+ combination on Nile tilapia, Oreochromis niloticus. The metal mixture under study has a detected 96-hour LC50 of 2.7% TU (Toxic unit). Fish were divided into four groups: Group 1, which served as the control group; Groups 2, 3, and 4 were exposed to 20% of the 96-hour LC50 for 30 days and fed on a conventional diet. Fish of Group 3 were supplemented with 20% vitamin C while fish of Group 4 were supplemented with 20% vitamin C as nanoparticles. The metals, levels in tissues of the liver and gills were examined, as well as the biochemical markers of metabolic processes in blood plasma. Fish from Group 2 displayed noticeable deteriorating conditions, followed by those from Group 3, whereas fish from Group 4 demonstrated noticeable good conditions across all examined criteria. Results showed that, while vitamin C nanoparticle proved to be more efficient, both vitamin C and its nanoparticles supplements had a positive impact on reducing the harmful effects of the studied metal mixture by chelating metal ions and scavenging free radicals.
ArticleNumber	24-035
Author	Flefel, Hassan E. Aly, Mohamed Y. M. Eldesouky, Mahmoud Rasly Abd-elrahman, Hatem H.
Author_xml	– sequence: 1 fullname: Abd-elrahman, Hatem H. organization: National Institute of Oceanography and Fisheries, Cairo, Egypt – sequence: 2 fullname: Aly, Mohamed Y. M. organization: National Institute of Oceanography and Fisheries, Cairo, Egypt – sequence: 3 fullname: Eldesouky, Mahmoud Rasly organization: Central Metallurgical Research and Development Institute, Cairo, Egypt – sequence: 4 fullname: Flefel, Hassan E. organization: Environmental Research Department, Theodor Bilharz Research Institute, Giza, Egypt
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Title	Protective Effects of Vitamin C Nanoparticles Supplemented Diet against Toxicity of Fe2+ and Mn2+ Mixture on Nile Tilapia; Oreochromis niloticus
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