New treatment options for pulmonary arterial hypertension — the first selective IP-receptor agonist selexipag
Pulmonary arterial hypertension (PAH) is a rare chronic life-threatening disease. The treatment standards for PAH patients emphasize the need for early intervention and achievement of all treatment goals with the use of monotherapy or combinations. To date, strong evidence has been obtained that com...
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Published in: | Kardiovaskuli͡a︡rnai͡a︡ terapii͡a︡ i profilaktika Vol. 18; no. 6; pp. 80 - 87 |
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Language: | English |
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Abstract | Pulmonary arterial hypertension (PAH) is a rare chronic life-threatening disease. The treatment standards for PAH patients emphasize the need for early intervention and achievement of all treatment goals with the use of monotherapy or combinations. To date, strong evidence has been obtained that combination therapy with PAH-specific medications can significantly inhibit the development of the disease. Therefore, in modern guidelines, combination therapy is considered as a treatment standard for a significant proportion of patients with PAH. This publication presents a modern view of the selexipag practical using in early combination therapy in patients with PAH. |
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AbstractList | Pulmonary arterial hypertension (PAH) is a rare chronic life-threatening disease. The treatment standards for PAH patients emphasize the need for early intervention and achievement of all treatment goals with the use of monotherapy or combinations. To date, strong evidence has been obtained that combination therapy with PAH-specific medications can significantly inhibit the development of the disease. Therefore, in modern guidelines, combination therapy is considered as a treatment standard for a significant proportion of patients with PAH. This publication presents a modern view of the selexipag practical using in early combination therapy in patients with PAH. |
Author | Martynyuk, T. V. Ivanov, K. I. Ilyin, N. V. |
Author_xml | – sequence: 1 givenname: N. V. orcidid: 0000-0001-6747-1585 surname: Ilyin fullname: Ilyin, N. V. organization: Republican Hospital № 1 — National Center of Medicine – sequence: 2 givenname: K. I. orcidid: 0000-0002-4084-6612 surname: Ivanov fullname: Ivanov, K. I. organization: Republican Hospital № 1 — National Center of Medicine – sequence: 3 givenname: T. V. orcidid: 0000-0002-9022-8097 surname: Martynyuk fullname: Martynyuk, T. V. organization: National Medical Research Center of Cardiology |
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Cites_doi | 10.1007/s40256-016-0209-9 10.1183/13993003.02493-2016 10.1002/ejhf.1375 10.2146/ajhp160798 10.1183/09031936.00137511 10.1056/NEJMoa1413687 10.26442/00403660.2019.01.000024 10.1093/eurheartj/ehv317 10.1056/NEJMoa1503184 |
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SubjectTerms | combination therapy pulmonary arterial hyperten¬sion selexipag specific therapy |
Title | New treatment options for pulmonary arterial hypertension — the first selective IP-receptor agonist selexipag |
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