New treatment options for pulmonary arterial hypertension — the first selective IP-receptor agonist selexipag

Pulmonary arterial hypertension (PAH) is a rare chronic life-threatening disease. The treatment standards for PAH patients emphasize the need for early intervention and achievement of all treatment goals with the use of monotherapy or combinations. To date, strong evidence has been obtained that com...

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Published in:Kardiovaskuli͡a︡rnai͡a︡ terapii͡a︡ i profilaktika Vol. 18; no. 6; pp. 80 - 87
Main Authors: Ilyin, N. V., Ivanov, K. I., Martynyuk, T. V.
Format: Journal Article
Language:English
Published: SILICEA-POLIGRAF» LLC 22-12-2019
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Abstract Pulmonary arterial hypertension (PAH) is a rare chronic life-threatening disease. The treatment standards for PAH patients emphasize the need for early intervention and achievement of all treatment goals with the use of monotherapy or combinations. To date, strong evidence has been obtained that combination therapy with PAH-specific medications can significantly inhibit the development of the disease. Therefore, in modern guidelines, combination therapy is considered as a treatment standard for a significant proportion of patients with PAH. This publication presents a modern view of the selexipag practical using in early combination therapy in patients with PAH.
AbstractList Pulmonary arterial hypertension (PAH) is a rare chronic life-threatening disease. The treatment standards for PAH patients emphasize the need for early intervention and achievement of all treatment goals with the use of monotherapy or combinations. To date, strong evidence has been obtained that combination therapy with PAH-specific medications can significantly inhibit the development of the disease. Therefore, in modern guidelines, combination therapy is considered as a treatment standard for a significant proportion of patients with PAH. This publication presents a modern view of the selexipag practical using in early combination therapy in patients with PAH.
Author Martynyuk, T. V.
Ivanov, K. I.
Ilyin, N. V.
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  organization: National Medical Research Center of Cardiology
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CitedBy_id crossref_primary_10_1080_13880209_2021_2005636
crossref_primary_10_38109_2225_1685_2020_2_54_60
crossref_primary_10_38109_2075_082X_2024_1_21_28
Cites_doi 10.1007/s40256-016-0209-9
10.1183/13993003.02493-2016
10.1002/ejhf.1375
10.2146/ajhp160798
10.1183/09031936.00137511
10.1056/NEJMoa1413687
10.26442/00403660.2019.01.000024
10.1093/eurheartj/ehv317
10.1056/NEJMoa1503184
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Snippet Pulmonary arterial hypertension (PAH) is a rare chronic life-threatening disease. The treatment standards for PAH patients emphasize the need for early...
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SubjectTerms combination therapy
pulmonary arterial hyperten¬sion
selexipag
specific therapy
Title New treatment options for pulmonary arterial hypertension — the first selective IP-receptor agonist selexipag
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