A new siloxane embedded benzalkonium chloride-based skin protectant (fiteBac Germicidal Skin Softening Gel) for use against insect bites and related dermal infections
Abstract fiteBac Skin Softening Gel, widely used as a cosmetic, contains the anti-infective benzalkonium chloride embedded in siloxane quaternary ammonium compounds, but does not contain alcohol. It thus serves well for skin protection combined with local anti-infective activity. As it does not pene...
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Published in: | Revista medica del hospital general de mexico s.s.a Vol. 81; no. 3; pp. 115 - 121 |
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Abstract | Abstract fiteBac Skin Softening Gel, widely used as a cosmetic, contains the anti-infective benzalkonium chloride embedded in siloxane quaternary ammonium compounds, but does not contain alcohol. It thus serves well for skin protection combined with local anti-infective activity. As it does not penetrate the skin, no systemic toxic side effects are expected, and more than 3 years of practical use have not revealed any adverse reactions. We have tested in a pilot study the usefulness of fiteBac Skin Softening Gel against skin lesions following insect bites various in nature as well as a few other ailments (e.g. fungus-related intertrigo). Of the 23 cases tested, all but one responded to the treatment with complete resolution of skin lesions within a few days up to a week. The only exception was a case of suspected tick bite with local arthritic symptoms. In the latter, a combination of the fiteBac gel treatment with subsequent local administration of ibuprofen gel also resulted in complete remission of dermatitis and arthritis. We thus recommend wider use of this cosmetic/anti-infective agent for the prevention and treatment of insect bites to prevent subsequent infectious complications (such as, for instance, Lyme disease). |
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AbstractList | Abstract fiteBac Skin Softening Gel, widely used as a cosmetic, contains the anti-infective benzalkonium chloride embedded in siloxane quaternary ammonium compounds, but does not contain alcohol. It thus serves well for skin protection combined with local anti-infective activity. As it does not penetrate the skin, no systemic toxic side effects are expected, and more than 3 years of practical use have not revealed any adverse reactions. We have tested in a pilot study the usefulness of fiteBac Skin Softening Gel against skin lesions following insect bites various in nature as well as a few other ailments (e.g. fungus-related intertrigo). Of the 23 cases tested, all but one responded to the treatment with complete resolution of skin lesions within a few days up to a week. The only exception was a case of suspected tick bite with local arthritic symptoms. In the latter, a combination of the fiteBac gel treatment with subsequent local administration of ibuprofen gel also resulted in complete remission of dermatitis and arthritis. We thus recommend wider use of this cosmetic/anti-infective agent for the prevention and treatment of insect bites to prevent subsequent infectious complications (such as, for instance, Lyme disease). fiteBac Skin Softening Gel, widely used as a cosmetic, contains the anti-infective benzalkonium chloride embedded in siloxane quaternary ammonium compounds, but does not contain alcohol. It thus serves well for skin protection combined with local anti-infective activity. As it does not penetrate the skin, no systemic toxic side effects are expected, and more than 3 years of practical use have not revealed any adverse reactions. We have tested in a pilot study the usefulness of fiteBac Skin Softening Gel against skin lesions following insect bites various in nature as well as a few other ailments (e.g. fungus-related intertrigo). Of the 23 cases tested, all but one responded to the treatment with complete resolution of skin lesions within a few days up to a week. The only exception was a case of suspected tick bite with local arthritic symptoms. In the latter, a combination of the fiteBac gel treatment with subsequent local administration of ibuprofen gel also resulted in complete remission of dermatitis and arthritis. We thus recommend wider use of this cosmetic/anti-infective agent for the prevention and treatment of insect bites to prevent subsequent infectious complications (such as, for instance, Lyme disease). El gel fiteBac suave para piel, ha sido ampliamente empleado como cosmético, contiene cloruro de benzalconio y está integrado con compuestos de amoniaco cuaternario en silicona como anti-infeccioso, pero no contiene alcohol. Por lo tanto, sirve para la protección de la piel combinado con una actividad local anti-infecciosa. Como ésta no penetra la piel, no se esperan efectos secundarios, y en más de tres años de su aplicación no se han revelado reacciones adversas. Se ha probado en un estudio piloto la utilidad del gel suavizante de piel en lesiones causadas por piquetes de insectos de diversa naturaleza, así como en otros padecimientos. (ej. micosis-relacionada con intertrigo). De 23 casos, todos menos uno respondió al tratamiento con la resolución total de las lesiones en la piel en unos cuantos días a una semana. La única excepción fue un caso con sospecha de mordedura de garrapata y síntomas de artritis local. Este último, la combinación del tratamiento con gel fiteBac y aplicación posterior de gel de ibuprofeno ayudó a la completa remisión de dermatitis y artritis. Por lo anterior, se recomienda un uso más amplio de este agente cosmético/anti-infeccioso para la prevención y tratamiento de picaduras de insectos para evitar complicaciones infecciosas subsecuentes. (Como, por ejemplo, la enfermedad de Lyme). fiteBac Skin Softening Gel, widely used as a cosmetic, contains the anti-infective benzalkonium chloride embedded in siloxane quaternary ammonium compounds, but does not contain alcohol. It thus serves well for skin protection combined with local anti-infective activity. As it does not penetrate the skin, no systemic toxic side effects are expected, and more than 3 years of practical use have not revealed any adverse reactions.We have tested in a pilot study the usefulness of fiteBac Skin Softening Gel against skin lesions following insect bites various in nature as well as a few other ailments (e.g. fungus-related intertrigo). Of the 23 cases tested, all but one responded to the treatment with complete resolution of skin lesions within a few days up to a week. The only exception was a case of suspected tick bite with local arthritic symptoms. In the latter, a combination of the fiteBac gel treatment with subsequent local administration of ibuprofen gel also resulted in complete remission of dermatitis and arthritis.We thus recommend wider use of this cosmetic/anti-infective agent for the prevention and treatment of insect bites to prevent subsequent infectious complications (such as, for instance, Lyme disease). Resumen: El gel fiteBac suave para piel, ha sido ampliamente empleado como cosmético, contiene cloruro de benzalconio y está integrado con compuestos de amoniaco cuaternario en silicona como anti-infeccioso, pero no contiene alcohol. Por lo tanto, sirve para la protección de la piel combinado con una actividad local anti-infecciosa. Como ésta no penetra la piel, no se esperan efectos secundarios, y en más de tres años de su aplicación no se han revelado reacciones adversas.Se ha probado en un estudio piloto la utilidad del gel suavizante de piel en lesiones causadas por piquetes de insectos de diversa naturaleza, así como en otros padecimientos. (ej. micosis-relacionada con intertrigo). De 23 casos, todos menos uno respondió al tratamiento con la resolución total de las lesiones en la piel en unos cuantos días a una semana. La única excepción fue un caso con sospecha de mordedura de garrapata y síntomas de artritis local. Este último, la combinación del tratamiento con gel fiteBac y aplicación posterior de gel de ibuprofeno ayudó a la completa remisión de dermatitis y artritis.Por lo anterior, se recomienda un uso más amplio de este agente cosmético/anti-infeccioso para la prevención y tratamiento de picaduras de insectos para evitar complicaciones infecciosas subsecuentes. (Como, por ejemplo, la enfermedad de Lyme). Keywords: Germicidal hand gel, Insect bites, Skin infections, Palabras clave: Gel germicida para piel, Picaduras de insectos, Infecciones dermicas |
Author | Krueger, Gerhard R.F Baban, Babak Niedworok, Clara Ablashi, Dharam V |
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Cites_doi | 10.1002/app.28670 10.1016/S1473-3099(14)71000-X 10.1007/s40257-016-0203-7 10.1111/j.1948-7134.2009.00007.x 10.1016/S0195-6701(08)60010-9 10.1016/j.wem.2013.08.007 10.1093/jme/tjx076 10.1021/am800046r 10.1097/00129804-200505000-00008 10.1002/app.25878 10.1002/app.30378 10.1021/am200250d 10.1016/j.jtv.2016.07.002 10.1097/CCM.0b013e31822f09c0 |
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Keywords | Insect bites Picaduras de insectos Skin infections Gel germicida para piel Infecciones dermicas Germicidal hand gel |
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Snippet | Abstract fiteBac Skin Softening Gel, widely used as a cosmetic, contains the anti-infective benzalkonium chloride embedded in siloxane quaternary ammonium... fiteBac Skin Softening Gel, widely used as a cosmetic, contains the anti-infective benzalkonium chloride embedded in siloxane quaternary ammonium compounds,... |
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SubjectTerms | Gel germicida para piel Germicidal hand gel Infecciones dermicas Insect bites Medical/Surgical Picaduras de insectos Skin infections |
Title | A new siloxane embedded benzalkonium chloride-based skin protectant (fiteBac Germicidal Skin Softening Gel) for use against insect bites and related dermal infections |
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