II : The effects of recombinant human insulin-like growth factor-1 on immunological recovery in the malnourished alcoholic rat

Immunological abnormalities are frequently observed in alcoholics with severe liver disease and are typically in association with immune abnormalities. Concomitantly, serum levels of insulin-like growth factor-1 (IGF-1) are frequently very low in these patients. Because IGF-1 is known to modulate bo...

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Bibliographic Details
Published in:	Alcoholism, clinical and experimental research Vol. 21; no. 9; pp. 1682 - 1689
Main Authors:	MENDENHALL, C. L, ROSELLE, G. A, GROSSMAN, C. J, GARTSIDE, P
Format:	Journal Article
Language:	English
Published:	Baltimore, MD Lippincott Williams & Wilkins 01-12-1997
Subjects:	Alcohol Drinking Alcoholism - drug therapy Alcoholism - immunology Alcoholism and acute alcohol poisoning Animals Biological and medical sciences Body Weight Disease Models, Animal Energy Intake Feeding Behavior Immunity - drug effects Insulin-Like Growth Factor I - pharmacology Insulin-Like Growth Factor I - therapeutic use Medical sciences Nutrition Disorders - drug therapy Nutrition Disorders - immunology Nutritional Status - drug effects Protein-Energy Malnutrition - drug therapy Protein-Energy Malnutrition - immunology Rats Rats, Inbred Lew Recombinant Proteins Spleen - drug effects Spleen - immunology T-Lymphocytes - drug effects T-Lymphocytes - immunology Thymus Gland - drug effects Thymus Gland - immunology Toxicology Animal model Immune response Rat Alcoholism Rodentia Nutrition disorder Hepatic disease Insulin like growth factor 1 Vertebrata Chemotherapy Mammalia Treatment Digestive diseases Malnutrition Nutritional status
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