Ventricular interdependent phenotype of mixed Cpc-pulmonary hypertension and HFpEF with normal left atrium: Impact on CPET metrics and clinical outcomes

Among 45 CpcPH/heart failure with preserved ejection fraction participants, 11 with normal left atrium (compared to 34 with abnormal left atrium,  < 0.05 for all) had low left ventricle (LV) transmural pressure (2.9 ± 2.4 vs. 6.2 ± 2.9 mmHg), and increased right ventricle (RV):LV ratio (2.41 ± 1....

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Published in:Pulmonary circulation Vol. 14; no. 4; p. e12449
Main Authors: Zampierollo-Jaramillo, Giovanna, Abed, Anas, El Shaer, Ahmed, Garcia-Arango, Mariana, Chen, Yimin, Tehrani, Babak, Tu, Wanxin, Arif, Abdul Wahab, Heffernan, Shannon, Esmaeeli, Amir, Sahai, Aditya, Runo, James, Baber, Aurangzeb, Masri, Sofia C, Raza, Farhan
Format: Journal Article
Language:English
Published: United States 01-10-2024
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Summary:Among 45 CpcPH/heart failure with preserved ejection fraction participants, 11 with normal left atrium (compared to 34 with abnormal left atrium,  < 0.05 for all) had low left ventricle (LV) transmural pressure (2.9 ± 2.4 vs. 6.2 ± 2.9 mmHg), and increased right ventricle (RV):LV ratio (2.41 ± 1.09 vs. 1.46 ± 0.66) and interventricular septal angle (149 ± 8 vs. 136 ± 10), indicating exaggerated ventricular interdependence from a dilated RV.
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ISSN:2045-8932
2045-8940
2045-8940
DOI:10.1002/pul2.12449