Fase aguda da doença de Chagas na Amazônia brasileira: estudo de 233 casos do Pará, Amapá e Maranhão observados entre 1988 e 2005
Foram estudados 233 casos de fase aguda da doença de Chagas, oriundos do Pará, Amapá e Maranhão, observados no período de 1988 a 2005, cento e sessenta deles retrospectivamente de 1988 a 2002 e setenta e três prospectivamente de 2003 a 2005. Entre os casos estudados 78,5% (183/233) faziam parte de s...
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| Published in: | Revista da Sociedade Brasileira de Medicina Tropical Vol. 41; no. 6; pp. 602 - 614 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | Portuguese |
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| Abstract | Foram estudados 233 casos de fase aguda da doença de Chagas, oriundos do Pará, Amapá e Maranhão, observados no período de 1988 a 2005, cento e sessenta deles retrospectivamente de 1988 a 2002 e setenta e três prospectivamente de 2003 a 2005. Entre os casos estudados 78,5% (183/233) faziam parte de surtos provavelmente por transmissão oral, acometendo em média 4 pessoas e 21,5% (50/233) eram casos isolados. Foram considerados casos agudos aqueles que apresentaram exames parasitológicos diretos (a fresco, gota espessa ou Quantitative Buffy Coat - QBC) e/ou IgM anti-Trypanosoma cruzi positivos. Foram feitos ainda xenodiagnósticos em 224 pacientes e hemoculturas em 213. Todos foram avaliados clinica e epidemiologicamente. As manifestações clínicas mais freqüentes foram febre (100%), cefaléia (92,3%), mialgia (84,1%), palidez (67%), dispnéia (58,4%), edema de membros inferiores (57,9%), edema de face (57,5%) dor abdominal (44,2%), miocardite (39,9%) e exantema (27%). O eletrocardiograma mostrou alterações de repolarização ventricular em 38,5% dos casos, baixa voltagem de QRS em 15,4% e desvio de SAQRS em 11,5%, extra-sístoles ventriculares em 5,8%, bradicardia em 5,8% e taquicardia em 5,8%, bloqueio de ramo direito em 4,8% e fibrilação atrial em 4,8%. A alteração mais freqüente vista no ecocardiograma foi o derrame pericárdico em 46,2% dos casos. Treze (5,6%) pacientes evoluíram para o óbito, 10 (76,9%) dos quais por comprometimento cardiovascular, dois por complicações de origem digestiva e um de causa mal definida. |
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| AbstractList | Foram estudados 233 casos de fase aguda da doença de Chagas, oriundos do Pará, Amapá e Maranhão, observados no período de 1988 a 2005, cento e sessenta deles retrospectivamente de 1988 a 2002 e setenta e três prospectivamente de 2003 a 2005. Entre os casos estudados 78,5% (183/233) faziam parte de surtos provavelmente por transmissão oral, acometendo em média 4 pessoas e 21,5% (50/233) eram casos isolados. Foram considerados casos agudos aqueles que apresentaram exames parasitológicos diretos (a fresco, gota espessa ou Quantitative Buffy Coat - QBC) e/ou IgM anti-Trypanosoma cruzi positivos. Foram feitos ainda xenodiagnósticos em 224 pacientes e hemoculturas em 213. Todos foram avaliados clinica e epidemiologicamente. As manifestações clínicas mais freqüentes foram febre (100%), cefaléia (92,3%), mialgia (84,1%), palidez (67%), dispnéia (58,4%), edema de membros inferiores (57,9%), edema de face (57,5%) dor abdominal (44,2%), miocardite (39,9%) e exantema (27%). O eletrocardiograma mostrou alterações de repolarização ventricular em 38,5% dos casos, baixa voltagem de QRS em 15,4% e desvio de SAQRS em 11,5%, extra-sístoles ventriculares em 5,8%, bradicardia em 5,8% e taquicardia em 5,8%, bloqueio de ramo direito em 4,8% e fibrilação atrial em 4,8%. A alteração mais freqüente vista no ecocardiograma foi o derrame pericárdico em 46,2% dos casos. Treze (5,6%) pacientes evoluíram para o óbito, 10 (76,9%) dos quais por comprometimento cardiovascular, dois por complicações de origem digestiva e um de causa mal definida. |
| Author | Pinto, Ana Yecê das Neves Valente, Sebastião Aldo Coura, José Rodrigues Ferreira Junior, Alberto Gomes Valente, Vera da Costa |
| AuthorAffiliation | Instituto Evandro Chagas Fundação Luiz Décourt Fundação Oswaldo Cruz |
| AuthorAffiliation_xml | – name: Fundação Oswaldo Cruz – name: Instituto Evandro Chagas – name: Fundação Luiz Décourt |
| Author_xml | – sequence: 1 givenname: Ana Yecê das Neves surname: Pinto fullname: Pinto, Ana Yecê das Neves organization: Instituto Evandro Chagas – sequence: 2 givenname: Sebastião Aldo surname: Valente fullname: Valente, Sebastião Aldo organization: Instituto Evandro Chagas – sequence: 3 givenname: Vera da Costa surname: Valente fullname: Valente, Vera da Costa organization: Instituto Evandro Chagas – sequence: 4 givenname: Alberto Gomes surname: Ferreira Junior fullname: Ferreira Junior, Alberto Gomes organization: Fundação Luiz Décourt – sequence: 5 givenname: José Rodrigues surname: Coura fullname: Coura, José Rodrigues organization: Fundação Oswaldo Cruz |
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| DocumentTitleAlternate | Acute phase of Chagas disease in the Brazilian Amazon region: study of 233 cases from Pará, Amapá and Maranhão observed between 1988 and 2005 |
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| Issue | 6 |
| Keywords | Amazônia Surtos de doenças Disease outbreaks Doenças emergentes Doença de Chagas aguda Acute of chagas disease Amazon region Emerging diseases |
| Language | Portuguese |
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| References | Orrego, LA; Lansetti, JC; Bozzini, JP; Martini, GJW 1980; 40 Miles, MA; Povoa, MM; Souza, AA; Lainson, R; Shaw, JJ; Ketteridge, DS 1981; 75 Souza, AAA; Nepomuceno, WNP; Lima, JAN; Póvoa, MM; Valente, SAS; Braga, RR; Correa, ZJC 1990; 20 Laranja, FS; Dias, E; Nobrega, G 1951; 38 Coura, JR; Fernandes, O; Arboleda, M; Barret, TV; Carrara, N; Degrave, W; Campbell, DA 1996; 90 Forattini, OP; Ferreira, OA; Silva, EOR; Rabello, EX 1979; 13 Viana, S; Farias, E; Lima, F; Batista, L; Vieira, A; Silva, L; Lobato, C; Nascimento, S; Chalub, S 1994; 27 Silva, NN; Clausel, DT; Nolibus, H; Mello, AL Ossanai J; Rapone, T; Snell, T 1968; 10 Miles, MA; Souza, AA; Povoa, MM 1981; 18 Lima, MZMS; Santos, IKFM; Souza, AAA; Naiff, RD; Czeco, YMT; Miles, MA 1985 Coura, JR 1990; 23 Pinto, AYN; Valente, SAS; Valente, VC 2004; 8 Shaw, JJ; Lainson, R; Fraiha, H 1969; 3 Dias, JCP 1982 Lugones, HS 2001 Jörg, ME; Freire, RS 1961; 4 Camandaroba, ELP; Lima, CMP; Andrade, SG 2002; 44 Ferreira, HO; Miziara, JL; Cançado, JR; Chuster, M 1985 Marcondes, MC; Borelli, P; Yoshida, N; Russo, M 2000; 2 Rassi, A; Rassi Jr, A; Rassi, GG; Brener, Z; Andrade, Z; Barral-Netto, M 2000 Deane, LM; Damasceno, RG 1961; 3 Torres, CM 1941; 36 Villela, E 1993; 4 Deane, LM 1964; 16 2005; 38 Valente, SAS; Valente, VC; Fraiha, H 1998; 94 Pinto, AYN; Harada, GS; Valente, VC; Abud, JE; Gomes, FD; Souza, GC; Valente, SAS 2001; 34 Parada, H; Carrasco, HA; Añez, N; Fuenmayor, C; Inglessis, I 1997; 60 Pinto, AYN; Valente, SAS; Lopes, R; Silva, O; Castro, T; Valente, VC 2003; 36 Barata, JMS; Rocha,, RM; Rodrigues,, Ferraz Filho NA 1988; 22 Combs, TP; Nagajyothi,, Mukherje S; Almeida, CJG; Jelicks, LA; Schubert, W; Lin, Y; Jayabalan, DS; Zhao, D; Braustein, VL; Landskroner-Eiger, S; Cordero, A; Factor, SM; Weiss, LM; Lisanti, MP; Tanowitz, HB; Scherer, PE 2005; 280 Añez, N; Carrasco, H; Parada, H; Crisante, G; Rojas, A; Gonzalez, N; Ramirez, JL; Guevara, P; Rivero, C; Borges, R; Scorza, JV 1999; 60 Silveira, FT; Dias, MG; Parda, P; Lobão, AO; Melo, GB 1979; 1 2005 Chagas, C 1924; 2 Coura, JR; Junqueira, AC; Giordano, CM; Funatsu, RK 1994; 36 2002; 80 Miles, MA; Arias, JR; Valente, SAS; Naiff, RD; Souza, AA; Povoa, MM; Lima, AN; Cedillos, RA 1983; 32 Valente, SAS; Crescente, JA; Valente, VC; Araújo, JEA; Lima, JAN 1993; 26 Andrade, LO; Andrews, NW 2005; 3 Rodrigues, IRC; Souza, AA; Terceros, R; Valente, S 1988; 21 Crescente, JA; Valente, SAS; Valente, VC; Araújo, JEA 1992; 25 Chagas, C 1916; 8 Rossi, MA; Ramos, S 1996; 66 Dorea, RCC 1981; 3 Laranja, FS; Dias, E; Nobrega, G; Miranda, A 1956; 14 Coura, JR; Junqueira, AC; Fernandes, O; Valente, SAS; Miles, MA 2002; 18 Deane, LM 1976; 9 Macedo, HS; Marçal Jr, O 2004; 3 |
| References_xml | – volume: 9 start-page: 143 year: 1976 end-page: 148 article-title: Tripanosomídeos de mamíferos da Região Amazônica IV: Hemoscopia e xenodiagnóstico de animais silvestres da Estrada Belém-Brasília publication-title: Revista do Instituto de Medicina Tropical de São Paulo contributor: fullname: Deane, LM – volume: 20 start-page: 137 year: 1990 end-page: 174 article-title: Doença de Chagas na Amazônia, ocorrência de um novo caso autóctone no Estado do Pará publication-title: Acta Amazônica contributor: fullname: Souza, AAA; Nepomuceno, WNP; Lima, JAN; Póvoa, MM; Valente, SAS; Braga, RR; Correa, ZJC – volume: 60 start-page: 215 year: 1999 end-page: 222 article-title: Acute Chagas disease in Western Venezuela: a clinical, seroparasitologic, and epidemiologic study publication-title: American Journal of Tropical Medicine and Hygiene contributor: fullname: Añez, N; Carrasco, H; Parada, H; Crisante, G; Rojas, A; Gonzalez, N; Ramirez, JL; Guevara, P; Rivero, C; Borges, R; Scorza, JV – volume: 80 start-page: 1 year: 2002 end-page: 17 article-title: Diretriz de interpretação do eletrocardiograma de repouso publication-title: Arquivos Brasileiros de Cardiologia – volume: 14 start-page: 1035 year: 1956 end-page: 1060 article-title: Chagas disease a clinical, epidemiologic, and pathologic study publication-title: Circulation contributor: fullname: Laranja, FS; Dias, E; Nobrega, G; Miranda, A – volume: 34 start-page: 413 year: 2001 end-page: 419 article-title: Cardiac attacks in patients with acute Chagas disease in a family micro-outbreak, in Abaetetuba, Brazilian Amazon publication-title: Revista da Sociedade Brasileira de Medicina Tropical contributor: fullname: Pinto, AYN; Harada, GS; Valente, VC; Abud, JE; Gomes, FD; Souza, GC; Valente, SAS – volume: 8 start-page: 37 year: 1916 end-page: 60 article-title: Tripanosomiase americana: Forma aguda da molestia publication-title: Memórias do Instituto Oswaldo Cruz contributor: fullname: Chagas, C – volume: 23 start-page: 67 year: 1990 end-page: 70 article-title: Chagas's disease as endemic to the Brazilian Amazon: risk or hypothesis? publication-title: Revista da Sociedade Brasileira de Medicina Tropical contributor: fullname: Coura, JR – volume: 16 start-page: 27 year: 1964 end-page: 48 article-title: Animal reservoirs of Trypanosoma cruzi in Brazil publication-title: Revista Brasileira de Malariolologia e Doenças Tropicais contributor: fullname: Deane, LM – volume: 280 start-page: 24085 year: 2005 end-page: 24094 article-title: The Adipocyte as an important target cell for Trypanosoma cruzi infection publication-title: Journal of Biological Chemistry contributor: fullname: Combs, TP; Nagajyothi,, Mukherje S; Almeida, CJG; Jelicks, LA; Schubert, W; Lin, Y; Jayabalan, DS; Zhao, D; Braustein, VL; Landskroner-Eiger, S; Cordero, A; Factor, SM; Weiss, LM; Lisanti, MP; Tanowitz, HB; Scherer, PE – volume: 26 start-page: 81 year: 1993 article-title: Observações sobre 5 casos agudos de doença de Chagas no Município de Afuá, Estado do Pará, 1992 publication-title: Revista da Sociedade Brasileira de Medicina Tropical contributor: fullname: Valente, SAS; Crescente, JA; Valente, VC; Araújo, JEA; Lima, JAN – volume: 60 start-page: 49 year: 1997 end-page: 54 article-title: Cardiac involvment is a constant finding in acute Chagas'disease: a clinical parasitological and histopathological study publication-title: International Journal of Cardiology contributor: fullname: Parada, H; Carrasco, HA; Añez, N; Fuenmayor, C; Inglessis, I – year: 1982 publication-title: Doença de Chagas em Bambuí, Minas Gerais, Brasil: Estudo-epidemiológico a partir da fase aguda, ente 1940 a 1982 contributor: fullname: Dias, JCP – volume: 13 start-page: 123 year: 1979 end-page: 146 article-title: Aspectos ecológicos da tripanosomíase americana: XIV - persistência e potencial de populações triatomínicas silvestres em região de intensa atividade agropecuária publication-title: Revista de Saúde Pública contributor: fullname: Forattini, OP; Ferreira, OA; Silva, EOR; Rabello, EX – volume: 18 start-page: 266 year: 1981 end-page: 278 article-title: Chagas'Disease in the Amazon Basin III Ecotopes of ten triatomine bug species (Hemiptera: Reduviidae) from the vicinity of Belém, Pará State publication-title: Brazilian Journal of Medical Entomology contributor: fullname: Miles, MA; Souza, AA; Povoa, MM – volume: 75 start-page: 667 year: 1981 end-page: 674 article-title: Chagas' Disease in the Amazon Basin: II. The distribution of Trypanosoma cruzi zymodemes 1 and 3 in Pará State, north Brazil publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene contributor: fullname: Miles, MA; Povoa, MM; Souza, AA; Lainson, R; Shaw, JJ; Ketteridge, DS – volume: 4 start-page: 33 year: 1993 end-page: 35 article-title: Moléstia de Chagas Descrição clínica, 1ª parte publication-title: Folha Médica contributor: fullname: Villela, E – volume: 94 start-page: 395 year: 1998 end-page: 398 article-title: Considerations on the epidemiology and transmission on Chagas disease in the Brazilian Amazon publication-title: Memórias do Instituto Oswaldo Cruz contributor: fullname: Valente, SAS; Valente, VC; Fraiha, H – volume: 2 start-page: 75 year: 1924 end-page: 77 article-title: Sobre a verificação do Trypanosoma cruzi em macacos do Pará (Chrysothrix sciureus). Nota prévia publication-title: Sciencia Medica contributor: fullname: Chagas, C – year: 1985 publication-title: Cardiopatia Chagásica contributor: fullname: Ferreira, HO; Miziara, JL; Cançado, JR; Chuster, M – volume: 32 start-page: 1251 year: 1983 end-page: 1259 article-title: Vertebrate hosts and vectors of Trypanosoma rangeli in the Amazon basin of Brazil publication-title: The American Journal of Tropical Medicine and Hygiene contributor: fullname: Miles, MA; Arias, JR; Valente, SAS; Naiff, RD; Souza, AA; Povoa, MM; Lima, AN; Cedillos, RA – volume: 36 start-page: 391 year: 1941 end-page: 404 article-title: Sobre a anatomia patológica da doença de Chagas publication-title: Memórias do Instituto Oswaldo Cruz contributor: fullname: Torres, CM – year: 1985 publication-title: Resumo contributor: fullname: Lima, MZMS; Santos, IKFM; Souza, AAA; Naiff, RD; Czeco, YMT; Miles, MA – volume: 90 start-page: 278 year: 1996 end-page: 279 article-title: Human infection by Trypanosoma rangeli in the Brazilian Amazon publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene contributor: fullname: Coura, JR; Fernandes, O; Arboleda, M; Barret, TV; Carrara, N; Degrave, W; Campbell, DA – volume: 21 start-page: 193 year: 1988 end-page: 197 article-title: Doença de Chagas na Amazônia I publication-title: Registro de 8 casos autóctones em Macapá. Revista da Sociedade Brasileira de Medicina Tropical contributor: fullname: Rodrigues, IRC; Souza, AA; Terceros, R; Valente, S – volume: 10 start-page: 265 year: 1968 end-page: 276 article-title: Surto epidêmico de doença de Chagas com provável contaminação oral publication-title: Revista do Instituto de Medicina Tropical de São Paulo contributor: fullname: Silva, NN; Clausel, DT; Nolibus, H; Mello, AL Ossanai J; Rapone, T; Snell, T – volume: 40 start-page: 56 year: 1980 end-page: 621 article-title: Hemoculture as a diagnostic method in Chagas disease publication-title: Medicine (B Aires) contributor: fullname: Orrego, LA; Lansetti, JC; Bozzini, JP; Martini, GJW – year: 2005 publication-title: Doença de Chagas aguda relacionada à ingestão de caldo de cana em Santa Catarina – volume: 1 start-page: 61 year: 1979 end-page: 62 article-title: Nono caso autóctone de doença de Chagas registrado no estado do Pará, Brasil (Nota prévia) publication-title: Hiléia Médica Belém contributor: fullname: Silveira, FT; Dias, MG; Parda, P; Lobão, AO; Melo, GB – volume: 66 start-page: 169 year: 1996 end-page: 176 article-title: Alterações microvasculares coronarianas na Doença de Chagas publication-title: Arquivos Brasileiros de Cardiologia contributor: fullname: Rossi, MA; Ramos, S – volume: 38 start-page: 30 year: 2005 article-title: Consenso Brasileiro em Doença de Chagas. Ministério da Saúde publication-title: Revista da Sociedade Brasileira de Medicina Tropical – volume: 22 start-page: 401 year: 1988 end-page: 410 article-title: Primeiro caso autóctone de tripanossomíase americana do estado do Acre (Brasil) e sua correlação com as cepas isoladas do caso humano e de triatomíneos silvestres da área publication-title: Revista de Saúde Pública contributor: fullname: Barata, JMS; Rocha,, RM; Rodrigues,, Ferraz Filho NA – volume: 3 start-page: 81 year: 1981 end-page: 109 article-title: Doença de Chagas na Amazônia: aspectos epidemiológicos regionais e considerações a propósito de um caso pediátrico publication-title: Hiléia Medica contributor: fullname: Dorea, RCC – volume: 3 start-page: 819 year: 2005 end-page: 823 article-title: The Trypanosoma Cruzi-Host-Cell Interplay: Location, Invasion, Retention publication-title: Nature Reviews Microbiology contributor: fullname: Andrade, LO; Andrews, NW – volume: 36 start-page: 363 year: 1994 end-page: 368 article-title: Chagas'disease in the Brazilian Amazon: I - A short review publication-title: Revista do Instituto de Medicina Tropical de São Paulo contributor: fullname: Coura, JR; Junqueira, AC; Giordano, CM; Funatsu, RK – volume: 3 start-page: 50 year: 2004 end-page: 66 article-title: Distribuição de vetores da doença de Chagas em nível domiciliar: um estudo na zona rural de Uberlândia (MG) publication-title: Caminhos da Geografia contributor: fullname: Macedo, HS; Marçal Jr, O – volume: 25 start-page: 67 year: 1992 article-title: Ocorrência de quatro casos agudos de Doença de Chagas na Vila de Icoaraci-PA publication-title: Revista da Sociedade Brasileira de Medicina Tropical contributor: fullname: Crescente, JA; Valente, SAS; Valente, VC; Araújo, JEA – volume: 27 start-page: 77 year: 1994 article-title: Doença de Chagas no Estado do Acre; registro de três casos de miocardiopatia chagásica aguda autóctone no Município de Rio Branco, 1994 publication-title: Revista da Sociedade Brasileira de Medicina Tropical contributor: fullname: Viana, S; Farias, E; Lima, F; Batista, L; Vieira, A; Silva, L; Lobato, C; Nascimento, S; Chalub, S – volume: 18 start-page: 171 year: 2002 end-page: 176 article-title: Emerging Chagas disease in Amazonian Brazil publication-title: Trends in Parasitology contributor: fullname: Coura, JR; Junqueira, AC; Fernandes, O; Valente, SAS; Miles, MA – volume: 44 start-page: 97 year: 2002 end-page: 103 article-title: Oral transmission of Chagas disease: importance of Trypanosoma cruzi biodeme in the intragastric experimental infection publication-title: Revista do Instituto de Medicina Tropical de São Paulo contributor: fullname: Camandaroba, ELP; Lima, CMP; Andrade, SG – volume: 4 start-page: 318 year: 1961 end-page: 350 article-title: Lipochagomata genii or Lipochagomata of the cheeks, characteristic lesions of acute Trypanosomiasis cruzi in children under there years of age publication-title: Acta Tropica contributor: fullname: Jörg, ME; Freire, RS – volume: 36 start-page: 381 year: 2003 article-title: Ocorrência de Tripanosomíase aguda familiar no município de Igarapé-Miri, Pará: gravidade de apresentação clínica em idosos publication-title: Revista da Sociedade Brasileira de Medicina Tropical contributor: fullname: Pinto, AYN; Valente, SAS; Lopes, R; Silva, O; Castro, T; Valente, VC – year: 2001 publication-title: Enfermedad de Chagas Diagnóstico de su faz aguda contributor: fullname: Lugones, HS – volume: 3 start-page: 153 year: 1969 end-page: 157 article-title: Considerações sobre a epidemiologia dos primeiros casos autóctones de Doença de Chagas registrados em Belém, Pará, Brasil publication-title: Revista de Saúde Pública contributor: fullname: Shaw, JJ; Lainson, R; Fraiha, H – volume: 38 start-page: 465 year: 1951 end-page: 484 article-title: Clinica y terapeutica de la enfermedad de Chagas publication-title: Prensa Medica Argentina contributor: fullname: Laranja, FS; Dias, E; Nobrega, G – volume: 2 start-page: 347 year: 2000 end-page: 352 article-title: Acute Trypanosoma cruzi infection is associated with anemia, thrombocytopenia, leukopenia and bone marrow hypoplasia: reversal by nifurtimox treatment publication-title: Microbes and infection/Institut Pasteur 2000 contributor: fullname: Marcondes, MC; Borelli, P; Yoshida, N; Russo, M – start-page: 431 year: 2000 publication-title: Trypanosoma cruzi e Doença de Chagas contributor: fullname: Rassi, A; Rassi Jr, A; Rassi, GG; Brener, Z; Andrade, Z; Barral-Netto, M – volume: 8 start-page: 454 year: 2004 end-page: 60 article-title: Emerging acute Chagas disease in Amazonian Brazil: case reports with serious cardiac involvement publication-title: Brazilian Journal of Infectious Disease contributor: fullname: Pinto, AYN; Valente, SAS; Valente, VC – volume: 3 start-page: 61 year: 1961 end-page: 70 article-title: Tripanosomídeos de mamíferos da Região Amazônica II: Tripanosomas de macacos da Zona do Salgado, Estado do Pará publication-title: Revista do Instituto de Medicina Tropical de São Paulo contributor: fullname: Deane, LM; Damasceno, RG |
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| Snippet | Foram estudados 233 casos de fase aguda da doença de Chagas, oriundos do Pará, Amapá e Maranhão, observados no período de 1988 a 2005, cento e sessenta deles... |
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| Title | Fase aguda da doença de Chagas na Amazônia brasileira: estudo de 233 casos do Pará, Amapá e Maranhão observados entre 1988 e 2005 |
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