cDNA cloning and sequence analysis of pluripotency genes in tree shrews (Tupaia belangeri)

In this paper, partial sequences of the tree shrew (Tupaia belangeri) Klf4, Sox2, and c-Myc genes were cloned and sequenced, which were 382, 612, and 485 bp in length and encoded 127, 204, and 161 amino acids, respectively. Whereas, their cDNA sequence identities with those of human were 89%, 98%, a...

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Published in:Dōngwùxué yánjiū Vol. 34; no. 2; p. 127
Main Authors: Wang, Cai-Yun, Ma, Yun-Han, He, Da-Jian, Yang, Shi-Hua
Format: Journal Article
Language:Chinese
English
Published: China 01-04-2013
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Abstract In this paper, partial sequences of the tree shrew (Tupaia belangeri) Klf4, Sox2, and c-Myc genes were cloned and sequenced, which were 382, 612, and 485 bp in length and encoded 127, 204, and 161 amino acids, respectively. Whereas, their cDNA sequence identities with those of human were 89%, 98%, and 89%, respectively. Their phylogenetic tree results indicated different topologies and suggested individual evolutional pathways. These results can facilitate further functional studies.
AbstractList In this paper, partial sequences of the tree shrew (Tupaia belangeri) Klf4, Sox2, and c-Myc genes were cloned and sequenced, which were 382, 612, and 485 bp in length and encoded 127, 204, and 161 amino acids, respectively. Whereas, their cDNA sequence identities with those of human were 89%, 98%, and 89%, respectively. Their phylogenetic tree results indicated different topologies and suggested individual evolutional pathways. These results can facilitate further functional studies.
Author Ma, Yun-Han
He, Da-Jian
Wang, Cai-Yun
Yang, Shi-Hua
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/23572363$$D View this record in MEDLINE/PubMed
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Tree shrew
Klf4
c-Myc
Sequence analysis
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Snippet In this paper, partial sequences of the tree shrew (Tupaia belangeri) Klf4, Sox2, and c-Myc genes were cloned and sequenced, which were 382, 612, and 485 bp in...
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SubjectTerms Amino Acid Sequence
Animals
Base Sequence
Cattle
Cloning, Molecular
DNA, Complementary - genetics
Female
Humans
Male
Mammals - classification
Mammals - genetics
Mice
Molecular Sequence Data
Open Reading Frames
Phylogeny
Proteins - genetics
Rats
Sequence Alignment
Tupaia - genetics
Title cDNA cloning and sequence analysis of pluripotency genes in tree shrews (Tupaia belangeri)
URI https://www.ncbi.nlm.nih.gov/pubmed/23572363
Volume 34
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