Correlation between Estrogen Levels with Lipid Profile in Menopause Women in West Sumatera

• Published in: Open access Macedonian journal of medical sciences Vol. 7; no. 13; pp. 2084 - 2087
• Main Authors: Ariadi, Ariadi, Jamsari, Jamsari, Yanwirasti, Yanwirasti, Siregar, Muhammad Fidel Ganis, Yusrawati, Yusrawati
• Format: Journal Article
• Language: English
• Published: Macedonia Republic of Macedonia 06-08-2019
• Subjects: Basic Science; HDL; Triglyceride; LDL; Menopause; Estrogen; Total Cholesterol
• ISSN: 1857-9655; 1857-9655
• DOI: 10.3889/oamjms.2019.627

Menopause is a condition where women had not experienced menstruation for 12 consecutive cycles. At menopause period, there is alteration in women reproductive cycle where estrogen decreased and lipid status altered.
This study is aimed to understand the association of estrogen level and lipid status in menopause women.
This study was an observational study with cross-sectional design underwent in Obstetrics and Gynecology Polyclinic Dr M. Djamil Hospital, Padang to examine estrogen level and lipid level in 107 menopause women aged between 40-60 years old. The study was conducted for 6 months. The relationship between estrogen level and lipid profile was done using correlation test and p-value < 0.05 is significant.
There was no significant correlation between estrogen and total cholesterol (p = 0.146), LDL (p = 0.496), HDL (p = 0.172) and triglyceride (p = 0.296) in menopause women. There was negative correlation between estrogen with total cholesterol (r = -0.141; p = 0.146), HDL (r = -0.133; p = 0.172) and triglyceride (r = -0.1; p = 0.296) and a little positive correlation with LDL (r = 0.06; p = 0.496). Estrogen levels are not related to total Cholesterol, LDL, HDL, and triglyceride in menopause women.
Estrogen levels did not correlate with lipid status in menopause women in West Sumatera.