Obstructive sleep apnea syndrome in Parkinson’s disease: Preliminary results

• Published in: Sleep medicine Vol. 14; p. e112
• Main Authors: Neto, M. Sobreira, Pereira, M, Sobreira, E, França Fernandes, R, Tumas, V, Eckeli, A
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01-12-2013
• Subjects: Neurology; Sleep Medicine
• ISSN: 1389-9457; 1878-5506
• DOI: 10.1016/j.sleep.2013.11.246

Introduction the prevalence of Obstructive Sleep Apnea Syndrome (OSAS) among patients with Parkinson’s Disease (PD) changes from 20% to 66%. OSAS also shows different characteristics in those patients as compared to general population. Objectives: to estimate the prevalence and characteristics of OSAS in patients with PD. Materials and methods Methods and patients : Patients were consecutively evaluated at a third level Outpatient Clinics for Movement Disorders, through the following clinical scales: PD Sleep Scale validated for the Brazilian population (PDSS-Br), Epworth‘s daytime sleepiness scale, quality of life questionnaire in PD (PDQ-39), unified PD rating scale (UPDRS), Hoehn & Yahr’s modified evaluation scale and Schwab & England‘s functional evaluation scale. All patients were submitted to polysomnography and diagnose of OSAS was defined according to the 2nd International Classification of Sleep Disorders. Results Seventy third (73) patients have been included so far, among whom we have found a prevalence of 61.6% of OSAS (45 patients), of mild or moderate severity in 86.6%. OSAS patients had higher age than those without OSAS ( p = 0.004). The mean score in Epworth‘s scale was higher among OSAS patients ( p = 0.05). Snore was the prevalent symptom in the group of OSAS patients (74.5%), showing a sensitivity of 80%. Apneas witnessed by partners were the most specific symptom, ranking 92%. We did not find significant differences between the groups with and without OSAS in regard to PDSS-Br, PDQ-39, UPDRS), Hoehn & Yahr’s modified evaluation scale and Schwab & England’s functional evaluation scale. Conclusion OSAS is a prevalent sleep disorder among PD patients, in whom it is found in higher aging people and is associated to greater daytime sleepiness, in comparison to non-OSAS PD patients. Snore is the most sensitive symptom and apneas witnessed by the partner the most specific symptom in PD patients with OSAS. Acknowledgements FAEPA (Fundação de Apoio ao Ensino, Pesquisa e Assistência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo) CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior).