pH-dependent Substrate Preference of Pig Heart Lipoamide Dehydrogenase Varies with Oligomeric State

Cycling of intracellular pH has recently been shown to play a critical role in ischemia-reperfusion injury. Ischemia-reperfusion also leads to mitochondrial matrix acidification and dysfunction. However, the mechanism by which matrix acidification contributes to mitochondrial dysfunction, oxidative...

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Bibliographic Details

Published in:	The Journal of biological chemistry Vol. 280; no. 16; pp. 16106 - 16114
Main Authors:	Klyachko, Natalia L., Shchedrina, Valentina A., Efimov, Alexander V., Kazakov, Sergey V., Gazaryan, Irina G., Kristal, Bruce S., Brown, Abraham M.
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 22-04-2005 American Society for Biochemistry and Molecular Biology
Online Access:	Get full text
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