Clinical characteristics in a cohort of patients with chronic inflammatory demyelinating polyneuropathy: a retrospective study

• Published in: Revista mexicana de neurociencia Vol. 25; no. 2; pp. 29 - 34
• Main Authors: Alvarado-Garcia, Marco A., Marquez-Vargas, Mitzi G., Millan-Padilla, Jesus, Olivares-de la Torre, Hector, Hernández-Juárez, Leticia M., Bazán-Rodríguez, Lisette
• Format: Journal Article
• Language: English
• Published: Academia Mexicana de Neurología A.C 04-04-2024
• Subjects: Clinical Neurology; Neurosciences; Functional status; Outcome characteristics; Treatment; Polineuropatía; Polineuropatía desmielizante inflamatoria crónica; Tratamiento; Polyneuropathy; Estado funcional; Chronic inflammatory demyelinating polyneuropathy; Características de resultado
• ISSN: 2604-6180
• DOI: 10.24875/RMN.23000055

Abstract Objective: The objective of the study is to evaluate the chronic inflammatory demyelinating polyneuropathy (CIDP) clinical spectrum in a cohort of Mexican patients who benefit from social security. Methods: A retrospective study of CIDP patients from 2010 to 2021. We documented neurological deficits, electrophysiological and laboratory parameters, diagnostic characteristics, disease activity, and clinical outcomes. Results: 36 cases met the criteria of the EAN/PNS 2021, the mean age was 58.25 ± 10.10 years, 50% were women, and 69.4% used intravenous immunoglobulin (IVIG). Concerning functional status, 63.9% had an independent walk and 86.1% had mild weakness in manual skills. The analysis of functional status showed better results in the IVIG treatment group. Conclusions: Similar to previous literature reports, 50% of our patients had stable active disease. Considering the heterogeneity of the disease, more research about treatment initiation and long-term results is warranted.