Targeting MTHFD2 in Acute Myeloid Leukemia

Alterations in differentiation pathways contribute to the development of acute myeloid leukemia (AML). Differentiation therapy with all-trans retinoic acid (ATRA) has dramatically altered the treatment of acute promyelocytic leukemia, transforming it from a nearly fatal disease to a curable one. We...

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Bibliographic Details

Published in:	Blood Vol. 126; no. 23; p. 443
Main Authors:	Pikman, Yana, Puissant, Alexandre, Alexe, Gabriela, Furman, Andrew, Frumm, Stacey, Ross, Linda, Chen, Liying, Fenouille, Nina, Bassil, Christopher F., Lewis, Caroline A, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Kung, Andrew L, Vader Heiden, Matthew, Hemann, Michael T., Banerji, Versha, Stegmaier, Kimberly
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 03-12-2015
Online Access:	Get full text
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