Synchronous Hepatocellular Carcinoma and Cholangiocellular Carcinoma on 18F-FDG PET/CT

• Published in: Molecular imaging and radionuclide therapy Vol. 27; no. 3; pp. 136 - 137
• Main Authors: Erdoğan, Ezgi Başak, Türk, Hacı Mehmet, Tekçe, Ertuğrul, Aydın, Mehmet
• Format: Journal Article
• Language: English
• Published: Türkiye Nükleer Tıp Derneği 01-10-2018; Galenos Publishing
• Subjects: Interesting Image; Tıp; Ankara; Türkiye; cholangiocellular carcinoma; 18F-FDG PET/BT; 18F-FDG PET/CT; Synchronous tumors; hepatosellüler karsinoma; hepatocellular carcinoma; Senkron tümörler; kolanjiosellüler karsinoma
• ISSN: 2146-1414; 2147-1959
• DOI: 10.4274/mirt.93723

A 43-year-old male patient presented with a mass lesion on the right liver lobe, segment 5, in radiological imaging and elevated
alpha-fetoprotein levels (323 ng/mL) compatible with hepatocellular carcinoma (HCC). Positron emission tomography/
computed tomography (PET/CT) images showed background level 18F-FDG uptake in the mass lesion. In addition, a secondary
focus of increased 18F-FDG uptake was detected on the left liver lobe, segment 2, approximately 1,5 cm in diameter.
Histopathological examination revealed HCC in the larger mass lesion with a lower 18F-FDG uptake, and cholangiocellular
carcinoma in the smaller mass lesion with a higher 18F-FDG uptake. To our knowledge, this is the first case report of two
histopathologically different primary malignant liver tumors in two distinct segments of the liver detected by PET/CT.