The Safety and Efficacy of Targeted Virus Specific Cytotoxic T-Lymphocytes (VST) Manufactured By the IFN-g Cytokine Capture System (CCS) for the Treatment of Refractory Adenovirus (ADV), Cytomegalovirus (CMV), Epstein Barr Virus (EBV) and BK Virus (BKV) in Children, Adolescents and Young Adults (CAYA) after Allogenic Hematopoietic Stem Cell Transplantation (Allo-HSCT), Solid Organ Transplantation (SOT), or with Primary Immunodeficiency (PID) (IND# 17449)

Viral infection remains a major cause of morbidity and mortality after allo-HSCT (Bollard/Heslop Blood 2016). Antibiotics for treatment of viral infection in immunocompromised patients are limited in efficacy and associated with toxicity (Gerdemann BBMT 2004; Sili Cytother 2012). Increasing evidence...

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Bibliographic Details

Published in:	Biology of blood and marrow transplantation Vol. 26; no. 3; pp. S72 - S73
Main Authors:	Flower, Allyson, Ayello, Janet, Harrison, Lauren, Morris, Erin, Sturhahn, Meghan, Maryamchik, Elena, Wang, Yongping, O'Donnell, Lynn, Abu-Arja, Rolla, Lee, Dean, Talano, Julie-An M., Johnson, Bryon D, Cairo, Mitchell S.
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01-03-2020
Online Access:	Get full text
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