Effects of Cardiac Resynchronization Therapy on a Six-minute Walk Test, Maximal Inspiratory Pressure and Peak Expiratory Flow in Patients with Heart Failure: A Longitudinal Study

• Published in: International journal of cardiovascular sciences Vol. 35; no. 5; pp. 690 - 695
• Main Authors: Alves, Christiane Rodrigues, Chermont, Sergio S. M. C., Reis, Christiane Wiefels, Nascimento, Erivelton A., Ribeiro, Mario Luiz, Ribeiro, Fernanda, Mesquita, Evandro Tinoco, Mesquita, Claudio Tinoco
• Format: Journal Article
• Language: English
• Published: Sociedade Brasileira de Cardiologia 01-10-2022
• Subjects: CARDIAC & CARDIOVASCULAR SYSTEMS; Heart Failure; Maximal Inspiratory Pressures; Walk Test; Cardiac Resynchronization Therapy
• ISSN: 2359-4802; 2359-5647; 2359-5647
• DOI: 10.36660/ijcs.20190158

Abstract Background: Cardiac resynchronization therapy (CRT) is an effective treatment for patients with heart failure. Objective: To evaluate the response of CRT in maximal inspiratory pressure (MIP), peak expiratory flow (PEF), and exercise tolerance as determined by the six-minute walk test (6MWT) in patients with HF. Methods: This study used the 6MWT and Manovacuometer to assess functional capacity in relation to activities of daily living, in which fatigue and dyspnea are common. Results: After six months of CRT, this study identified improvements in the 6MWT, p<0.05; MIP, p=0.01; and PEF, p=0.03. Conclusion: After CRT, this study showed a significant improvement in MIP, PEF, and exercise tolerance. However, further studies are warranted to demonstrate the relevance of these findings.