Posterior Scleritis Associated with Late-Onset Takayasu Arteritis: A Case Report

• Published in: Ocular immunology and inflammation pp. 1 - 4
• Main Authors: Bertolani, Yann, Goncharova, Tetiana, Kirkegaard-Biosca, Eric, Angrill-Valls, Julia, Anglada-Masferrer, Natalia, Gutuleac, Liliana, Distefano, Laura, Zapata, Miguel Ángel
• Format: Journal Article
• Language: English
• Published: England 10-10-2024
• Subjects: tocilizumab; Choroidal folds; Takayasu arteritis; posterior scleritis; T sign
• ISSN: 0927-3948; 1744-5078; 1744-5078
• DOI: 10.1080/09273948.2024.2413894

To describe a rare case of posterior scleritis associated with late-onset Takayasu arteritis.
A case report of a 75-year-old female presenting with posterior scleritis, eventually diagnosed with late-onset Takayasu arteritis was described. Several medical evaluation visits were conducted, including ophthalmological and rheumatological follow-up. Multiple diagnostic tests were carried out, and the cornerstones of the treatment were corticosteroids and the IL-6 inhibitor tocilizumab.
The patient was admitted to our hospital's emergency room with right unilateral eyelid edema, chemosis and red eye. She had previously experienced two episodes that were misdiagnosed as preseptal cellulitis. The presence of choroidal folds and the T sign on the ultrasound exam were highly suggestive of posterior scleritis. Later, the patient was diagnosed with Takayasu arteritis, a type of large vessel vasculitis. Treatment with steroids was started, which was later switched to IL-6 inhibitors to achieve better control of the systemic disease.
Posterior scleritis is often misdiagnosed, necessitating high clinical suspicion. Multimodal diagnosis is important to establish an accurate diagnosis. Up to 34% of cases may be associated with a systemic disease. This is the first case described in the literature of posterior scleritis associated with late-onset Takayasu arteritis.