Microbiological End-Point Determination of Antibiotics
There is currently some concern regarding the possibility that consumption, by humans, of small quantities of veterinary antibiotics, present as residues in meat, might adversely alter the indigenous gut microflora. This study aimed to assess the potential effect on the human gut microflora of expos...
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| Published in: | Microbial ecology in health and disease Vol. 10; no. 1; pp. 3 - 11 |
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| Format: | Journal Article |
| Language: | English |
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Informa UK Ltd
1998
Taylor & Francis |
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| Abstract | There is currently some concern regarding the possibility that consumption, by humans, of small quantities of veterinary antibiotics, present as residues in meat, might adversely alter the indigenous gut microflora. This study aimed to assess the potential effect on the human gut microflora of exposure to low levels of tilmicosin and spiramycin. Four groups of 4 human-flora-associated rats were dosed for 5 days with either water, tilmicosin (400 or 120 |
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| AbstractList | There is currently some concern regarding the possibility that consumption, by humans, of small quantities of veterinary antibiotics, present as residues in meat, might adversely alter the indigenous gut microflora. This study aimed to assess the potential effect on the human gut microflora of exposure to low levels of tilmicosin and spiramycin. Four groups of 4 human-flora-associated rats were dosed for 5 days with either water, tilmicosin (400 or 120 |
| Author | C. J. Rumney, J. T. Coutts, J. S. Smith, I. R. Rowland |
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| CitedBy_id | crossref_primary_10_1006_rtph_1999_1300 crossref_primary_10_1080_089106001750462704 |
| Cites_doi | 10.1080/10408399209527575 10.1128/AAC.38.3.409 10.1016/0378-1135(93)90145-W 10.1258/002367788780746142 10.1128/AAC.31.4.587 10.1093/ajcn/33.11.2440 10.1016/0378-1135(93)90144-V 10.1111/j.1365-2672.1987.tb02415.x 10.1016/0278-6915(95)90774-K 10.3109/08910609509140098 10.1111/j.1365-2672.1993.tb05201.x 10.1080/01652176.1994.9694439 10.1093/carcin/14.1.79 |
| ContentType | Journal Article |
| Copyright | 1998 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1998 1998 The Author(s). Published by Taylor & Francis. 1998 |
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| References | Rumney CJ (CIT0008) 1995; 33 Hazenberg MP (CIT0011) 1981; 50 Mallett AK (CIT0012) 1987; 63 O'Rourke J (CIT0024) 1988; 22 Pecquet S (CIT0021) 1986; 29 Corpet DE (CIT0007) 1993; 35 Raibaud P (CIT0010) 1980; 33 Rumney CJ (CIT0018) 1993; 14 Ducluzeau R (CIT0016) 1984; 135 Andremont A (CIT0020) 1983; 148 CIT0014 Corpet DE (CIT0013) 1989; 8 CIT0015 Andremont A (CIT0027) 1991; 27 Corpet DE (CIT0006) 1993; 35 Rowland IR (CIT0017) 1993; 74 Corpet DE (CIT0022) 1987; 31 Vollaard EJ (CIT0001) 1994; 38 Boisseau J (CIT0009) 1989; 42 CIT0025 Thirty-eighth report of the Joint FAO (CIT0026) 1991; 815 Nord CE (CIT0004) 1993; 35 Rumney CJ (CIT0019) 1994; 7 Welling GW (CIT0023) 1980; 117 CIT0028 |
| References_xml | – volume: 7 start-page: 52 year: 1994 ident: CIT0019 publication-title: Micro-bial Ecology in Health and Disease contributor: fullname: Rumney CJ – ident: CIT0014 doi: 10.1080/10408399209527575 – volume: 148 start-page: 579 year: 1983 ident: CIT0020 publication-title: Tancrede C. Effect of ery-thromycin on microbial antagonisms: a study in gnotobiotic mice associated with a human faecal flora. J Infect Dis contributor: fullname: Andremont A – volume: 50 start-page: 95 year: 1981 ident: CIT0011 publication-title: Effects of the human intestinal flora in germ-free mice. J Appl Bacteriol contributor: fullname: Hazenberg MP – volume: 35 start-page: 37 issue: 1 year: 1993 ident: CIT0006 publication-title: Vet Hum Toxicol contributor: fullname: Corpet DE – volume: 38 start-page: 409 year: 1994 ident: CIT0001 publication-title: Antimi-crobial Agents and Chemotherapy doi: 10.1128/AAC.38.3.409 contributor: fullname: Vollaard EJ – volume: 35 start-page: 199 year: 1993 ident: CIT0007 publication-title: Vet Microbiol doi: 10.1016/0378-1135(93)90145-W contributor: fullname: Corpet DE – volume: 117 start-page: 57 year: 1980 ident: CIT0023 publication-title: Biochemical effects on germ-free mice of association with several strains of anaerobic bacteria. Journal of General Microbiology contributor: fullname: Welling GW – volume: 22 start-page: 297 year: 1988 ident: CIT0024 publication-title: Lab Anim doi: 10.1258/002367788780746142 contributor: fullname: O'Rourke J – volume: 31 start-page: 587 year: 1987 ident: CIT0022 publication-title: Antimicrobial Agents and Chemotherapy doi: 10.1128/AAC.31.4.587 contributor: fullname: Corpet DE – ident: CIT0025 – volume: 42 start-page: 58 year: 1989 ident: CIT0009 publication-title: J Vet Med contributor: fullname: Boisseau J – volume: 33 start-page: 2440 year: 1980 ident: CIT0010 publication-title: Am J Clin Nutrition doi: 10.1093/ajcn/33.11.2440 contributor: fullname: Raibaud P – volume: 35 start-page: 193 year: 1993 ident: CIT0004 publication-title: Vet Microbiol doi: 10.1016/0378-1135(93)90144-V contributor: fullname: Nord CE – volume: 63 start-page: 39 year: 1987 ident: CIT0012 publication-title: J Appl Bacteriol doi: 10.1111/j.1365-2672.1987.tb02415.x contributor: fullname: Mallett AK – volume: 8 start-page: 391 year: 1989 ident: CIT0013 publication-title: In vitro, in vivo and mathematical models. Reviews in Science Technology contributor: fullname: Corpet DE – volume: 815 start-page: 31 year: 1991 ident: CIT0026 publication-title: Evaluation of certain veteri-nary drug residues in food. WHO Technical Report Series contributor: fullname: Thirty-eighth report of the Joint FAO – volume: 29 start-page: 1047 year: 1986 ident: CIT0021 publication-title: Selective antimicrobial modulation of the intestinal tract by norfloxacin in human volunteers and in gnotobiotic mice associated with a human fecal flora. Antimicrobial Agents and Chemotherapy contributor: fullname: Pecquet S – volume: 33 start-page: 331 year: 1995 ident: CIT0008 publication-title: Food and Chemi-cal Toxicology doi: 10.1016/0278-6915(95)90774-K contributor: fullname: Rumney CJ – ident: CIT0015 doi: 10.3109/08910609509140098 – volume: 74 start-page: 667 year: 1993 ident: CIT0017 publication-title: J Appl Bacteriol doi: 10.1111/j.1365-2672.1993.tb05201.x contributor: fullname: Rowland IR – volume: 27 start-page: 355 year: 1991 ident: CIT0027 publication-title: Effect of oral spiramycin on the faecal and oral bacteria in human volun-teers. J Antimicrob Chemother contributor: fullname: Andremont A – ident: CIT0028 doi: 10.1080/01652176.1994.9694439 – volume: 135 start-page: 303 year: 1984 ident: CIT0016 publication-title: Effect of bran ingestion on the microbial faecal floras of human donors and of recipient gnotobiotic mice, and on the barrier effects exerted by these floras against various potentially pathogenic micro-bial strains. Ann Microbiol contributor: fullname: Ducluzeau R – volume: 14 start-page: 79 year: 1993 ident: CIT0018 publication-title: Carcinogenesis doi: 10.1093/carcin/14.1.79 contributor: fullname: Rumney CJ |
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| Title | Microbiological End-Point Determination of Antibiotics |
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