Biosynthesis of cupric oxide nanoparticles derived from pomegranate peel extract: A sustainable approach with antioxidant, antimicrobial, and photocatalytic capabilities

• Published in: Inorganic chemistry communications Vol. 168; p. 112862
• Main Authors: Bouricha, M’hamed, Hammoudi, Roukia, Rouibah, Maria, Khenfer, Sihem, Bissati Bouafia, Samia, Benlkhelfa, Hakim, Abdellah, Henni, Oussama, Bacha, Ouidad, Baka
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01-10-2024
• Subjects: Antimicrobial activity; Antioxidant activity; Cupric oxide nanoparticles; Green synthesis; Photocatalytic activity; Pomegranate peel extract; Photocatalytic activity; Cupric oxide nanoparticles; Antimicrobial activity; Green synthesis; Pomegranate peel extract; Antioxidant activity
• ISSN: 1387-7003
• DOI: 10.1016/j.inoche.2024.112862

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•Biosynthesis of CuO-NPs from pomegranate peel extract to promote eco-friendly production of nanoparticles.•Antimicrobial properties effective against bacteria and fungi, aiding infection control.•Potential in drug delivery, bioimaging, and tissue engineering.•Good photocatalytic activity for degrading organic pollutants under light.•Green synthesis methods reduce environmental impact and hazardous chemical use.
This study reports the biosynthesis of cupric oxide nanoparticles (CuO-NPs) using pomegranate (Punica granatum) extracts for biological and environmental applications. Characterization techniques including UV–visible spectroscopy, X-ray diffraction (XRD), Energy dispersive X-ray spectroscopy (EDX), and scanning electron microscopy (SEM) confirmed the formation of monoclinic CuO-NPs with spherical morphology and average size <100 nm. The CuO-NPs exhibited antioxidant activity with a half-maximal inhibitory concentration of 0.86 mg/ml by DPPH assay. Complete photocatalytic degradation of methylene blue dye was achieved, indicating their potential for environmental remediation. Antimicrobial tests showed inhibition zones ranging from 6–14 mm against pathogenic microbes at 150 µg/ml and 10 mm at 25 µg/ml, demonstrating the biocidal efficacy of the biosynthesized CuO-NPs.