Trends and outcomes of inpatient cardiac implantable electronic device transvenous lead extractions: a nationwide analysis

• Published in: Journal of interventional cardiac electrophysiology
• Main Authors: Khalil, Charl, Lazar, Sorin, Megaly, Michael, Mekritthikrai, Raktham, Vipparthy, Sharath C, Doukky, Rami, Mortada, Mohammad E, Huang, Henry D, Sharma, Parikshit S
• Format: Journal Article
• Language: English
• Published: Netherlands 06-08-2024
• Subjects: Sex differences; Lead extraction; Cardiac tamponade; Mortality; Transvenous
• ISSN: 1572-8595; 1572-8595
• DOI: 10.1007/s10840-024-01891-y

Higher rates of CIED implantations have been associated with an increased rate of lead failures and complications resulting in higher rates of transvenous lead extractions (TLE).
To assess the trends TLE admissions and evaluate the patient related predictors of safety outcomes.
National Readmission Database was queried to identify patients who underwent TLE from January 2016 to December 2019. We conducted a multivariate regression analysis to identify variables associated with in-hospital mortality in patients undergoing TLE. Additionally, we compared trends and outcomes of TLE among patients with prior sternotomy versus those without prior sternotomy and analyzed sex-based differences among patients undergoing TLE.
We identified 30,128 hospitalizations for TLE. The index admission in-hospital mortality rate was 3.21% with cardiac tamponade happening in 1.46% of the admissions. Age, infective endocarditis, CKD, congestive heart failure and anemia were associated with higher in-hospital mortality rates. There was a lower rate of in-hospital mortality in patients with history of prior sternotomy versus patients without (OR 0.72, CI: 0.59-0.87, p-value < 0.001). There was no difference in in-hospital mortality rate between males and females. Females had a shorter length and a higher cost of stay when compared to male gender.
TLE admissions continue to increase. Overall rates of mortality and complications are relatively low. Patients with prior sternotomy had better outcomes and less complications when compared to those without prior sternotomy. Female gender is associated with higher rates of cardiac tamponade, yet shorter length of stay with lower cost.