Acute lung pathology in the immunocompromised child
Children with compromised immune systems, whether due to primary or secondary immunodeficiencies, are susceptible to a broad spectrum of acute intrathoracic pathologies. These include infections, pulmonary edema, and malignancies. Pulmonary issues are common and perilous in this population, necessit...
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Published in: | Pediatric radiology |
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Abstract | Children with compromised immune systems, whether due to primary or secondary immunodeficiencies, are susceptible to a broad spectrum of acute intrathoracic pathologies. These include infections, pulmonary edema, and malignancies. Pulmonary issues are common and perilous in this population, necessitating prompt and precise diagnosis for effective management. This review aims to provide an overview of such conditions, focusing on the imaging appearances of the most prevalent acute lung conditions affecting immunocompromised children. It emphasizes the critical importance of an integrated clinical and radiological approach when diagnosing these acute pulmonary disease states. |
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AbstractList | Children with compromised immune systems, whether due to primary or secondary immunodeficiencies, are susceptible to a broad spectrum of acute intrathoracic pathologies. These include infections, pulmonary edema, and malignancies. Pulmonary issues are common and perilous in this population, necessitating prompt and precise diagnosis for effective management. This review aims to provide an overview of such conditions, focusing on the imaging appearances of the most prevalent acute lung conditions affecting immunocompromised children. It emphasizes the critical importance of an integrated clinical and radiological approach when diagnosing these acute pulmonary disease states. Children with compromised immune systems, whether due to primary or secondary immunodeficiencies, are susceptible to a broad spectrum of acute intrathoracic pathologies. These include infections, pulmonary edema, and malignancies. Pulmonary issues are common and perilous in this population, necessitating prompt and precise diagnosis for effective management. This review aims to provide an overview of such conditions, focusing on the imaging appearances of the most prevalent acute lung conditions affecting immunocompromised children. It emphasizes the critical importance of an integrated clinical and radiological approach when diagnosing these acute pulmonary disease states.Children with compromised immune systems, whether due to primary or secondary immunodeficiencies, are susceptible to a broad spectrum of acute intrathoracic pathologies. These include infections, pulmonary edema, and malignancies. Pulmonary issues are common and perilous in this population, necessitating prompt and precise diagnosis for effective management. This review aims to provide an overview of such conditions, focusing on the imaging appearances of the most prevalent acute lung conditions affecting immunocompromised children. It emphasizes the critical importance of an integrated clinical and radiological approach when diagnosing these acute pulmonary disease states. |
Author | Rutten, Caroline Manson, David |
Author_xml | – sequence: 1 givenname: David orcidid: 0000-0002-6797-8017 surname: Manson fullname: Manson, David email: david.manson@sickkids.ca, david.manson@sickkids.ca organization: Department of Medical Imaging, University of Toronto, Toronto, ON, Canada. david.manson@sickkids.ca – sequence: 2 givenname: Caroline orcidid: 0000-0001-5847-1313 surname: Rutten fullname: Rutten, Caroline organization: Department of Medical Imaging, University of Toronto, Toronto, ON, Canada |
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Cites_doi | 10.1053/ro.2000.6154 10.1016/S2213-2600(15)00202-7 10.2214/AJR.11.7027 10.1007/s00431-015-2518-4 10.1002/hon.3139 10.3390/jcm12186041 10.1186/s13244-019-0796-5 10.1002/jso.10231 10.1016/j.pcl.2010.01.011 10.1111/nyas.12849 10.1007/s10875-020-00769-8 10.1016/S1045-1870(05)80043-3 10.1111/j.1460-9592.2007.02279.x 10.1200/JCO.1999.17.3.796 10.1148/radiol.2482070988 10.1016/0022-3468(90)90195-F 10.1165/rcmb.2016-0290TR 10.1007/s002470000237 10.1002/mpo.1157 10.1093/cid/ciy723 10.1056/NEJM199508173330707 10.1053/j.sempedsurg.2006.03.005 10.1007/s00330-012-2558-3 10.1001/archpedi.154.2.190 10.1016/0003-4975(92)90100-I 10.1016/j.jaci.2020.10.020 10.1016/j.pcl.2020.09.003 10.1177/1089253215578931 10.1038/s41571-021-00474-4 10.1016/j.bbmt.2014.09.019 |
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Keywords | Infection Neoplasm Immunosuppression Child Lung Computerized tomography |
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