T Cells in Nasal Polyposis Demonstrate Hyporesponsiveness to Signaling through the T cell Receptor

Upregulation of CD107a surface expression, another T-cell activation endpoint, was decreased in polyp-associated CD8+ T cells following stimulation compared to T cells from donor PBL(p < 0.01).

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Bibliographic Details
Published in:	Journal of allergy and clinical immunology Vol. 125; no. 2; p. AB62
Main Authors:	Lehman, H.K, Bernstein, J.M, Bankert, R.B
Format:	Journal Article
Language:	English
Published:	St. Louis Mosby, Inc 01-02-2010 Elsevier Limited
Subjects:	Allergy and Immunology Flow cytometry Immune system Lymphocytes Phosphorylation T cell receptors
Online Access:	Get full text
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Description
Summary:	Upregulation of CD107a surface expression, another T-cell activation endpoint, was decreased in polyp-associated CD8+ T cells following stimulation compared to T cells from donor PBL(p < 0.01).
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2009.12.963