L-ASPARAGINASE INDUCED HYPOFIBRINOGENEMIA: A CASE REPORT

Anticancer therapy is always known to cause various side effects. L-asparaginase used in the treatment of adult T-cell lymphoblastic leukemia is anovel class of drug, an enzyme produced from plants as well as microorganisms except human. It is known to cause various adverse reactions including life-...

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Bibliographic Details
Published in:Asian journal of pharmaceutical and clinical research Vol. 10; no. 5; p. 11
Main Authors: Ommurugan, Balaji, Priya, Amita, Patil, Navin
Format: Journal Article
Language:English
Published: 01-05-2017
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Summary:Anticancer therapy is always known to cause various side effects. L-asparaginase used in the treatment of adult T-cell lymphoblastic leukemia is anovel class of drug, an enzyme produced from plants as well as microorganisms except human. It is known to cause various adverse reactions including life-threatening neurological complications and thrombotic disorders. Hence, we report a case of hypofibrinogenemia associated with L-asparaginase in a patient treated for T-cell adult lymphoblastic leukemia.Keywords: L-asparaginase, Hypofibrinogenemia, Adverse effect, Leukemia.
ISSN:0974-2441
0974-2441
DOI:10.22159/ajpcr.2017.v10i5.17320