The effect of mood disorders on the course of coronary heart disease: a modern model of pathogenesis of depression, pathophysiological and behavioral patterns

The effect of mood disorders on the course of coronary heart disease: a modern model of pathogenesis of depression, pathophysiological and behavioral patterns

The prevalence of depressive disorders at the population level is from 2,5 to 10% among patients with coronary heart disease - 20%. The presence of depressive disorders in patients with coronary artery disease leads to hypersympathicotonia decrease vagal activity, endothelial dysfunction and blood c...

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Bibliographic Details
Published in:CardioSomatika Vol. 5; no. 3-4; pp. 5 - 8
Main Authors: T. G Nonka, A. N Repin, T. N Sergienko
Format: Journal Article
Language:English
Published: Concilium Medicum 15-12-2014
Subjects:
coronary heart disease
depressive disorders
pathogenesis
Online Access:Get full text
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Summary:The prevalence of depressive disorders at the population level is from 2,5 to 10% among patients with coronary heart disease - 20%. The presence of depressive disorders in patients with coronary artery disease leads to hypersympathicotonia decrease vagal activity, endothelial dysfunction and blood coagulation system, weighing down the disease. The most significant theories of pathophysiological mechanism of increased mortality in patients with cardiovascular disease in combination with mood disorders are increased thrombus formation and disturbance of the autonomic regulation of heart rhythm.
ISSN:2221-7185
2658-5707
DOI:10.26442/CS45098