A254 SYNCHRONOUS GASTRIC ADENOCARCINOMA, MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA AND GASTROINTESTINAL STROMAL TUMOR

Abstract Background Presently, there is very little literature on the simultaneous existence of different types of gastric cancers. Aims We present a case of rare concomitant cancers (adenocarcinoma, mucosa-associated lymphoid tissue lymphoma and gastrointestinal stromal tumor) in the stomach. It is...

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Bibliographic Details
Published in:Journal of the Canadian Association of Gastroenterology Vol. 1; no. suppl_1; pp. 441 - 442
Main Authors: Adamowicz, B, Desilets, E, Bensoussan, M, Lamarre, L, Maniere, T
Format: Journal Article
Language:English
Published: US Oxford University Press 01-03-2018
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Summary:Abstract Background Presently, there is very little literature on the simultaneous existence of different types of gastric cancers. Aims We present a case of rare concomitant cancers (adenocarcinoma, mucosa-associated lymphoid tissue lymphoma and gastrointestinal stromal tumor) in the stomach. It is important for clinicians to be aware of the various presentations of gastric cancers, as it may alter the treatment and prognosis. Methods This is a case report. Results We present the case and histology of a H. pylori negative 70-year-old man with concomitant adenocarcinoma, mucosa-associated lymphoid tissue lymphoma (MALT) and gastrointestinal stromal tumor of the stomach who was successfully treated with total gastrectomy and oesophago-jejunostomy Roux-en-Y anastomosis. Conclusions Although H. pylori seems to play an important role in the pathogenesis of gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma (MALT), its role in the carcinogenesis of gastrointestinal stromal tumors is still unknown. In addition, the link between these tumours becomes more complex in H. pylori negative patients. Many authors have argued that the discovery of synchronous neoplasms in a single tissue is coincidence. It is for this reason that some physicians may underreport the incidence of concomitant tumours. It is important for clinicians to be aware of the various presentations of gastric cancers, as it may alter the treatment and prognosis. Funding Agencies None
ISSN:2515-2084
2515-2092
DOI:10.1093/jcag/gwy008.255