Retraction speed and chronic poststernotomy pain: A randomized controlled trial

• Published in: The Journal of thoracic and cardiovascular surgery
• Main Authors: Phelan, Rachel, Petsikas, Dimitri, Shelley, Jessica, Hopman, Wilma M, DuMerton, Deborah, Parry, Monica, Payne, Darrin, Allard, Rene, Cummings, Michael, Parlow, Joel L, Tanzola, Robert, Wang, Louie T S, Stewart, Craig, Saha, Tarit K
• Format: Journal Article
• Language: English
• Published: United States 30-11-2023
• Subjects: pain; HRQoL; health-related quality of life; coronary artery bypass graft; sternal retraction speed; CABG; chronic poststernotomy pain
• ISSN: 0022-5223; 1097-685X
• DOI: 10.1016/j.jtcvs.2023.11.037

Approximately 30% of patients develop chronic poststernotomy pain (CPSP) following cardiac surgery with sternal retraction. Risk factors have been described but no causal determinants identified. Investigators hypothesized that opening the sternum slowly would impart less force (and thereby less nerve/tissue damage) and translate to a reduced incidence of CPSP. The main objectives were to determine whether or not slower sternal retraction would reduce the incidence of CPSP and improve health-related quality of life.
Patients undergoing coronary artery bypass graft surgery were recruited to this randomized controlled trial. Patients were randomized to slow or standard retraction (ie, sternum opened over 15 minutes vs 30 seconds, respectively). Although the anesthesiologist and surgeon were aware of the randomization, the patients, assessors, and postoperative nursing staff remained blinded. Sternotomy pain and analgesics were measured in hospital. At 3, 6, and 12 months postoperatively, all patients completed the Medical Outcomes Survey Short Form and reported on CPSP and complications requiring rehospitalization. Thirty-day rehospitalizations and mortality were recorded.
In total, 326 patients consented to participate and 313 were randomized to slow (n = 159) versus standard retraction (n = 154). No clinically relevant differences were detected in acute pain, analgesic consumption, or the incidence of CPSP or health-related quality of life. Although the slow group had significantly more hospitalizations at 3 and 12 months postoperatively, the reasons were unrelated to retraction speed. No differences were observed in 30-day rehospitalizations or mortality.
All outcomes were consistent with previous reports, but no clinically significant differences were observed with retraction speed.